Format

Send to:

Choose Destination

Ryr2 ryanodine receptor 2, cardiac [ Mus musculus (house mouse) ]

Gene ID: 20191, updated on 30-May-2016
Official Symbol
Ryr2provided by MGI
Official Full Name
ryanodine receptor 2, cardiacprovided by MGI
Primary source
MGI:MGI:99685
See related
Ensembl:ENSMUSG00000021313
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RYR-2; 9330127I20Rik
Orthologs
Location:
13 4.38 cM; 13 A1-A2
Exon count:
108
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (11553099..12106945, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (11645370..12199212, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40666 Neighboring gene zona pellucida glycoprotein 4, pseudogene Neighboring gene ribosomal protein S7 pseudogene Neighboring gene predicted gene 10336 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adrenergic signaling in cardiomyocytes, organism-specific biosystem (from KEGG)
    Adrenergic signaling in cardiomyocytes, organism-specific biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
  • Adrenergic signaling in cardiomyocytes, conserved biosystem (from KEGG)
    Adrenergic signaling in cardiomyocytes, conserved biosystemCardiac myocytes express at least six subtypes of adrenergic receptor (AR) which include three subtypes of beta-AR (beta-1, beta-2, beta-3) and three subtypes of the alpha-1-AR (alpha-1A, alpha-1B, a...
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem (from KEGG)
    Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystemArrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may result in arrhythmia, heart failure, and sudden death. The hallmark pathological findings are prog...
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem (from KEGG)
    Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystemArrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may result in arrhythmia, heart failure, and sudden death. The hallmark pathological findings are prog...
  • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
    Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Cardiac conduction, organism-specific biosystem (from REACTOME)
    Cardiac conduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Cardiac muscle contraction, organism-specific biosystem (from KEGG)
    Cardiac muscle contraction, organism-specific biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
  • Cardiac muscle contraction, conserved biosystem (from KEGG)
    Cardiac muscle contraction, conserved biosystemContraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation...
  • Circadian entrainment, organism-specific biosystem (from KEGG)
    Circadian entrainment, organism-specific biosystemCircadian entrainment is a fundamental property by which the period of the internal biological clock is entrained by recurring exogenous signals, such that the organism's endocrine and behavioral rhy...
  • Circadian entrainment, conserved biosystem (from KEGG)
    Circadian entrainment, conserved biosystemCircadian entrainment is a fundamental property by which the period of the internal biological clock is entrained by recurring exogenous signals, such that the organism's endocrine and behavioral rhy...
  • Dilated cardiomyopathy, organism-specific biosystem (from KEGG)
    Dilated cardiomyopathy, organism-specific biosystemDilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contraction of the left or both ventricles that results in progressive heart failure and sudden cardiac d...
  • Dilated cardiomyopathy, conserved biosystem (from KEGG)
    Dilated cardiomyopathy, conserved biosystemDilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contraction of the left or both ventricles that results in progressive heart failure and sudden cardiac d...
  • Hypertrophic cardiomyopathy (HCM), organism-specific biosystem (from KEGG)
    Hypertrophic cardiomyopathy (HCM), organism-specific biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
  • Hypertrophic cardiomyopathy (HCM), conserved biosystem (from KEGG)
    Hypertrophic cardiomyopathy (HCM), conserved biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
  • Insulin secretion, organism-specific biosystem (from KEGG)
    Insulin secretion, organism-specific biosystemPancreatic beta cells are specialised endocrine cells that continuously sense the levels of blood sugar and other fuels and, in response, secrete insulin to maintain normal fuel homeostasis. Glucose-...
  • Ion channel transport, organism-specific biosystem (from REACTOME)
    Ion channel transport, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Ion homeostasis, organism-specific biosystem (from REACTOME)
    Ion homeostasis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Muscle contraction, organism-specific biosystem (from REACTOME)
    Muscle contraction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Myometrial Relaxation and Contraction Pathways, organism-specific biosystem (from WikiPathways)
    Myometrial Relaxation and Contraction Pathways, organism-specific biosystem
    Myometrial Relaxation and Contraction Pathways
  • Oxytocin signaling pathway, organism-specific biosystem (from KEGG)
    Oxytocin signaling pathway, organism-specific biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Oxytocin signaling pathway, conserved biosystem (from KEGG)
    Oxytocin signaling pathway, conserved biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Pancreatic secretion, organism-specific biosystem (from KEGG)
    Pancreatic secretion, organism-specific biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Pancreatic secretion, conserved biosystem (from KEGG)
    Pancreatic secretion, conserved biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • SIDS Susceptibility Pathways, organism-specific biosystem (from WikiPathways)
    SIDS Susceptibility Pathways, organism-specific biosystemIn this model, we provide an integrated view of Sudden Infant Death Syndrome (SIDS) at the level of implicated tissues, signaling networks and genetics. The purpose of this model is to serve as an ov...
  • Stimuli-sensing channels, organism-specific biosystem (from REACTOME)
    Stimuli-sensing channels, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Transmembrane transport of small molecules, organism-specific biosystem (from REACTOME)
    Transmembrane transport of small molecules, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • cAMP signaling pathway, organism-specific biosystem (from KEGG)
    cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cAMP signaling pathway, conserved biosystem (from KEGG)
    cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-induced calcium release activity ISO
Inferred from Sequence Orthology
more info
 
calcium-release channel activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium-release channel activity ISO
Inferred from Sequence Orthology
more info
 
calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
calmodulin binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
organic cyclic compound binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase A catalytic subunit binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase A regulatory subunit binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein self-association IMP
Inferred from Mutant Phenotype
more info
PubMed 
ryanodine-sensitive calcium-release channel activity IDA
Inferred from Direct Assay
more info
PubMed 
ryanodine-sensitive calcium-release channel activity ISO
Inferred from Sequence Orthology
more info
 
scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
suramin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
BMP signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
Purkinje myocyte to ventricular cardiac muscle cell signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
calcium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transport IPI
Inferred from Physical Interaction
more info
PubMed 
calcium ion transport ISO
Inferred from Sequence Orthology
more info
 
calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
 
calcium-mediated signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium-mediated signaling using intracellular calcium source ISO
Inferred from Sequence Orthology
more info
 
canonical Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
cardiac muscle contraction ISO
Inferred from Sequence Orthology
more info
 
cardiac muscle hypertrophy IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to caffeine IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to caffeine ISO
Inferred from Sequence Orthology
more info
 
cellular response to epinephrine stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosolic calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
detection of calcium ion ISO
Inferred from Sequence Orthology
more info
 
embryonic heart tube morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of protein localization to endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
left ventricular cardiac muscle tissue morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
manganese ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of calcium-transporting ATPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of heart rate IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of sequestering of calcium ion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of the force of heart contraction ISO
Inferred from Sequence Orthology
more info
 
regulation of AV node cell action potential ISO
Inferred from Sequence Orthology
more info
 
regulation of SA node cell action potential ISO
Inferred from Sequence Orthology
more info
 
regulation of atrial cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
 
regulation of cardiac muscle contraction ISO
Inferred from Sequence Orthology
more info
 
regulation of cardiac muscle contraction by calcium ion signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
regulation of heart rate IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of heart rate ISO
Inferred from Sequence Orthology
more info
 
regulation of ventricular cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
 
release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
PubMed 
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
response to caffeine IDA
Inferred from Direct Assay
more info
PubMed 
response to caffeine ISO
Inferred from Sequence Orthology
more info
 
response to calcium ion ISO
Inferred from Sequence Orthology
more info
 
response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
response to magnesium ion ISO
Inferred from Sequence Orthology
more info
 
response to muscle activity ISO
Inferred from Sequence Orthology
more info
 
response to muscle stretch ISO
Inferred from Sequence Orthology
more info
 
response to redox state ISO
Inferred from Sequence Orthology
more info
 
sarcoplasmic reticulum calcium ion transport ISO
Inferred from Sequence Orthology
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
type B pancreatic cell apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
type B pancreatic cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
ventricular cardiac muscle cell action potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
A band ISO
Inferred from Sequence Orthology
more info
 
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
Z disc ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with Z disc ISO
Inferred from Sequence Orthology
more info
 
calcium channel complex IDA
Inferred from Direct Assay
more info
PubMed 
calcium channel complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IC
Inferred by Curator
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
sarcolemma ISO
Inferred from Sequence Orthology
more info
 
sarcomere IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
sarcoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
smooth endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ryanodine receptor 2
Names
calcium release channel
cardiac muscle ryanodine receptor
cardiac muscle ryanodine receptor-calcium release channel
ryanodine receptor type 2
type 2 ryanodine receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023868.2NP_076357.2  ryanodine receptor 2

    See identical proteins and their annotated locations for NP_076357.2

    Status: VALIDATED

    Source sequence(s)
    AC131329, AC159208, AF295105, BB387101, BC059061, BU921357, U23755
    Consensus CDS
    CCDS49206.1
    UniProtKB/Swiss-Prot
    E9Q401
    UniProtKB/TrEMBL
    Q60835, Q80ZZ5
    Related
    ENSMUSP00000021750, ENSMUST00000021750
    Conserved Domains (14) summary
    smart00472
    Location:286376
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:654805
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10861218
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14121559
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:47114829
    Ion_trans; Ion transport protein
    pfam01365
    Location:451655
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26992793
    RyR; RyR domain
    pfam02815
    Location:226406
    MIR; MIR domain
    pfam06459
    Location:43324598
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:38253947
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:9219
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    pfam13499
    Location:40324086
    EF-hand_7; EF-hand domain pair
    pfam14070
    Location:39544003
    YjfB_motility; Putative motility protein
    cl08302
    Location:40294084
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

    Range
    11553099..12106945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244296.1XP_011242598.1  

    Conserved Domains (14) summary
    smart00472
    Location:279369
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:647798
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10791211
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14051552
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:46924810
    Ion_trans; Ion transport protein
    pfam01365
    Location:444648
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26922786
    RyR; RyR domain
    pfam02815
    Location:219399
    MIR; MIR domain
    pfam06459
    Location:43134579
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:38063928
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:9212
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    pfam13499
    Location:40134067
    EF-hand_7; EF-hand domain pair
    pfam14070
    Location:39353984
    YjfB_motility; Putative motility protein
    cl08302
    Location:40104065
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  2. XM_006516610.1XP_006516673.1  

    Conserved Domains (14) summary
    smart00472
    Location:286376
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:654805
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10861218
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14121559
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:47304848
    Ion_trans; Ion transport protein
    pfam01365
    Location:451655
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26992793
    RyR; RyR domain
    pfam02815
    Location:226406
    MIR; MIR domain
    pfam06459
    Location:43514617
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:38443966
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:9219
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    pfam13499
    Location:40514105
    EF-hand_7; EF-hand domain pair
    pfam14070
    Location:39734022
    YjfB_motility; Putative motility protein
    cl08302
    Location:40484103
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  3. XM_006516614.2XP_006516677.1  

    Conserved Domains (8) summary
    smart00472
    Location:286376
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:654805
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10861218
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14121559
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam01365
    Location:451655
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26992793
    RyR; RyR domain
    pfam02815
    Location:226406
    MIR; MIR domain
    pfam08709
    Location:9219
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  4. XM_011244297.1XP_011242599.1  

    Conserved Domains (8) summary
    smart00472
    Location:286376
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:654805
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10861218
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14121559
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam01365
    Location:451655
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26992793
    RyR; RyR domain
    pfam02815
    Location:226406
    MIR; MIR domain
    pfam08709
    Location:9219
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
  5. XM_006516615.2XP_006516678.1  

    Conserved Domains (8) summary
    smart00472
    Location:286376
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:654805
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10861218
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14121559
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam01365
    Location:451655
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26992793
    RyR; RyR domain
    pfam02815
    Location:226406
    MIR; MIR domain
    pfam08709
    Location:9219
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

Alternate Mm_Celera

Genomic

  1. AC_000035.1 Alternate Mm_Celera

    Range
    11467020..12025871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)