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FOXD4L1 forkhead box D4-like 1 [ Homo sapiens (human) ]

Gene ID: 200350, updated on 26-May-2016
Official Symbol
FOXD4L1provided by HGNC
Official Full Name
forkhead box D4-like 1provided by HGNC
Primary source
HGNC:HGNC:18521
See related
Ensembl:ENSG00000184492 HPRD:17010; MIM:611084; Vega:OTTHUMG00000131359
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FOXD5; bA395L14.1
Summary
This gene is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and may play a role in human cancer. This gene lies in a region of chromosome 2 that surrounds the site where two ancestral chromosomes fused to form human chromosome 2. This region is duplicated elsewhere in the human genome, primarily in subtelomeric and pericentromeric locations, thus mutiple copies of this gene have been found. [provided by RefSeq, Jul 2008]
Orthologs
Location:
2q13
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 2 NC_000002.12 (113499084..113501150)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (114256661..114258727)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927400 Neighboring gene Ig kappa chain V-I region Walker-like Neighboring gene uncharacterized LOC105373568 Neighboring gene COBW domain containing 2 Neighboring gene uncharacterized LOC101927424 Neighboring gene PGM5P4 antisense RNA 1 Neighboring gene phosphoglucomutase 5 pseudogene 4

Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
forkhead box protein D4-like 1
Names
FOXD4-like 1
forkhead box D4 like 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012184.4NP_036316.1  forkhead box protein D4-like 1

    See identical proteins and their annotated locations for NP_036316.1

    Status: REVIEWED

    Source sequence(s)
    AK122950, AK125398, AY344639
    Consensus CDS
    CCDS2117.1
    UniProtKB/Swiss-Prot
    Q9NU39
    UniProtKB/TrEMBL
    B3KVK3
    Related
    ENSP00000302756, OTTHUMP00000162048, ENST00000306507, OTTHUMT00000254148
    Conserved Domains (1) summary
    cd00059
    Location:107184
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p2 Primary Assembly

    Range
    113499084..113501150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 Alternate CHM1_1.1

    Range
    114261281..114263347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)