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Slc22a8 solute carrier family 22 (organic anion transporter), member 8 [ Mus musculus (house mouse) ]

Gene ID: 19879, updated on 21-May-2016
Official Symbol
Slc22a8provided by MGI
Official Full Name
solute carrier family 22 (organic anion transporter), member 8provided by MGI
Primary source
MGI:MGI:1336187
See related
Ensembl:ENSMUSG00000063796
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oat3; Roct
Orthologs
Location:
19; 19 A
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (8591254..8611835)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (8665744..8686325)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 (organic anion transporter), member 19 pseudogene Neighboring gene solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 pseudogene Neighboring gene predicted gene, 36394 Neighboring gene solute carrier family 22 (organic anion transporter), member 6 Neighboring gene RIKEN cDNA 9830166K06 gene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
inorganic anion exchanger activity IBA
Inferred from Biological aspect of Ancestor
more info
 
inorganic anion exchanger activity ISO
Inferred from Sequence Orthology
more info
 
organic anion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
protein kinase C binding ISO
Inferred from Sequence Orthology
more info
 
quaternary ammonium group transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glutathione transport ISO
Inferred from Sequence Orthology
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
quaternary ammonium group transport ISO
Inferred from Sequence Orthology
more info
 
response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
solute carrier family 22 member 8
Names
organic anion transporter 3
reduced in osteosclerosis transporter
solute carrier family 22, member 8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164634.1NP_001158106.1  solute carrier family 22 member 8

    See identical proteins and their annotated locations for NP_001158106.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC125136, AK031962, AK044336, BE944759, BU615016
    Consensus CDS
    CCDS29537.1
    UniProtKB/Swiss-Prot
    O88909
    Related
    ENSMUSP00000131045, ENSMUST00000170817
    Conserved Domains (2) summary
    cd06174
    Location:124492
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11503
    2A0119; cation transport protein
  2. NM_001164635.1NP_001158107.1  solute carrier family 22 member 8

    See identical proteins and their annotated locations for NP_001158107.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AK031962, AK044336, BB843926, BE944759
    Consensus CDS
    CCDS29537.1
    UniProtKB/Swiss-Prot
    O88909
    Conserved Domains (2) summary
    cd06174
    Location:124492
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11503
    2A0119; cation transport protein
  3. NM_031194.5NP_112471.3  solute carrier family 22 member 8

    See identical proteins and their annotated locations for NP_112471.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC125136, AK031962, AK044336, BB622154, BE944759
    Consensus CDS
    CCDS29537.1
    UniProtKB/Swiss-Prot
    O88909
    Related
    ENSMUSP00000010251, ENSMUST00000010251
    Conserved Domains (2) summary
    cd06174
    Location:124492
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11503
    2A0119; cation transport protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

    Range
    8591254..8611835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247171.1XP_011245473.1  

    See identical proteins and their annotated locations for XP_011245473.1

    UniProtKB/Swiss-Prot
    O88909
    Conserved Domains (2) summary
    cd06174
    Location:124492
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11503
    2A0119; cation transport protein
  2. XM_006526787.2XP_006526850.1  

    Conserved Domains (2) summary
    cd06174
    Location:124412
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11423
    2A0119; cation transport protein

Alternate Mm_Celera

Genomic

  1. AC_000041.1 Alternate Mm_Celera

    Range
    8349417..8369998
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)