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Rapsn receptor-associated protein of the synapse [ Mus musculus (house mouse) ]

Gene ID: 19400, updated on 8-May-2016
Official Symbol
Rapsnprovided by MGI
Official Full Name
receptor-associated protein of the synapseprovided by MGI
Primary source
MGI:MGI:99422
See related
Ensembl:ENSMUSG00000002104 Vega:OTTMUSG00000014338
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Raps; 43kDa; Nraps; rapsyn
Orthologs
Location:
2 E1; 2 50.44 cM
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (91035466..91045729)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (90875784..90885886)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, mitochondrial 1 Neighboring gene CUGBP, Elav-like family member 1 Neighboring gene 60S acidic ribosomal protein P1-like Neighboring gene proteasome (prosome, macropain) 26S subunit, ATPase 3 Neighboring gene solute carrier family 39 (metal ion transporter), member 13 Neighboring gene predicted gene, 39875

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC130501

Gene Ontology Provided by MGI

Function Evidence Code Pubs
acetylcholine receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
acetylcholine receptor binding ISO
Inferred from Sequence Orthology
more info
 
ionotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein anchor ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of neuromuscular synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of postsynaptic membrane organization ISO
Inferred from Sequence Orthology
more info
 
skeletal muscle acetylcholine-gated channel clustering ISO
Inferred from Sequence Orthology
more info
 
synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission, cholinergic ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
neuromuscular junction ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
43 kDa receptor-associated protein of the synapse
Names
43 kDa postsynaptic protein
43kDa acetylcholine receptor-associated protein
acetylcholine receptor-associated 43 kDa protein
receptor-associated protein of the synapse, 43 kDa

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009023.3NP_033049.2  43 kDa receptor-associated protein of the synapse

    See identical proteins and their annotated locations for NP_033049.2

    Status: VALIDATED

    Source sequence(s)
    BY709325, J03962
    Consensus CDS
    CCDS16422.1
    UniProtKB/Swiss-Prot
    P12672
    Related
    ENSMUSP00000054150, OTTMUSP00000015159, ENSMUST00000050323, OTTMUST00000033854
    Conserved Domains (6) summary
    pfam10579
    Location:180
    Rapsyn_N; Rapsyn N-terminal myristoylation and linker region
    COG0457
    Location:9239
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00162
    Location:363405
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam13424
    Location:204278
    TPR_12; Tetratricopeptide repeat
    cl14649
    Location:138236
    BRO1_Alix_like; Protein-interacting Bro1-like domain of mammalian Alix and related domains
    sd00006
    Location:127151
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    91035466..91045729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499017.2XP_006499080.1  

    Related
    ENSMUSP00000107072, OTTMUSP00000015161, ENSMUST00000111445, OTTMUST00000033856
    Conserved Domains (6) summary
    pfam10579
    Location:180
    Rapsyn_N; Rapsyn N-terminal myristoylation and linker region
    COG0457
    Location:9239
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00162
    Location:345387
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam13424
    Location:204278
    TPR_12; Tetratricopeptide repeat
    cl14649
    Location:138236
    BRO1_Alix_like; Protein-interacting Bro1-like domain of mammalian Alix and related domains
    sd00006
    Location:127151
    TPR; TPR repeat [structural motif]

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    92420152..92430248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)