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    Rad51ap1 RAD51 associated protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 19362, updated on 26-Feb-2013
    Official Symbol
    Rad51ap1provided by MGI
    Official Full Name
    RAD51 associated protein 1provided by MGI
    Primary source
    MGI:1098224
    See related
    Ensembl:ENSMUSG00000030346; Vega:OTTMUSG00000024111
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAB22; 2510006L10Rik
    Location :
    6 F3; 6 61.92 cM
    Sequence :
    Chromosome: 6; NC_000072.6 (126923419..126939555, complement)
    See Rad51ap1 in Epigenomics, MapViewer

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene A kinase (PRKA) anchor protein 3 Neighboring gene dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 Neighboring gene metaxin 1 pseudogene Neighboring gene DNA segment, Chr 6, Wayne State University 163, expressed Neighboring gene predicted gene 6487

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Tang F, et al. PLoS One, 2011. PMID 21731673.
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    3. Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Dray E, et al. Proc Natl Acad Sci U S A, 2011 Mar 1. PMID 21307306.
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693.

    See all (22) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. RAD51AP1 foci colocalize with a subset of DMC1 foci in spermatocytes.
      Title: Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1).
    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    Products Interactant Other Gene Complex Source Pubs Description
    NP_033039.1 NP_035364.1 Rad51    BIND  PubMed RAB22 interacts with RAD51. This interaction was modeled on a demonstrated interaction between mouse RAB22 and human RAD51. 

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    DNA recombination IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Preferred Names
    RAD51-associated protein 1
    Names
    RAD51-associated protein 1
    RAD51-interacting protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009013.3 → NP_033039.2  RAD51-associated protein 1

      Status: PROVISIONAL

      Source sequence(s)
      AK011379
      Consensus CDS
      CCDS39644.1
      UniProtKB/Swiss-Prot
      Q8C551
      Related
      ENSMUSP00000107841, OTTMUSP00000028651, ENSMUST00000112221, OTTMUST00000058977

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p1 C57BL/6J

      Range
      126923419..126939555, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000028.1 Alternate Mm_Celera

      Range
      128597764..128618928, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01057356.1 (4405..15877) None
    genomic AAHY01057357.1 None
    genomic AAHY01057358.1 None
    genomic AC165085.3 (36420..51883) None
    genomic CH466523.1 EDK99847.1 mixed
      EDK99848.1 mixed
      EDK99849.1 mixed
    mRNA AK010920.1 None C57BL/6J
    mRNA AK011379.1 BAB27579.1 C57BL/6J
    mRNA AK077829.1 BAC37025.1 C57BL/6J
    mRNA AK079525.1 BAC37671.1 C57BL/6J
    mRNA AK166703.1 None C57BL/6J
    mRNA BC003738.1 AAH03738.1 CZECHII
    mRNA BC022586.1 None
    mRNA BC040809.1 None
    mRNA U93583.1 AAB91541.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C551.2 GenPept UniProtKB/Swiss-Prot:Q8C551

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
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      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).

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