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KRT24 keratin 24 [ Homo sapiens (human) ]

Gene ID: 192666, updated on 26-May-2016
Official Symbol
KRT24provided by HGNC
Official Full Name
keratin 24provided by HGNC
Primary source
HGNC:HGNC:18527
See related
Ensembl:ENSG00000167916 HPRD:09668; MIM:607742; Vega:OTTHUMG00000133372
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
K24; KA24
Summary
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jun 2009]
Orthologs
Location:
17q21.2
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 17 NC_000017.11 (40697991..40703750, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (38854243..38860002, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin 222 Neighboring gene uncharacterized LOC105371775 Neighboring gene keratin 223 pseudogene Neighboring gene keratin 25

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ20261, MGC138169, MGC138173

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
intermediate filament IEA
Inferred from Electronic Annotation
more info
 
intermediate filament cytoskeleton IDA
Inferred from Direct Assay
more info
 
Preferred Names
keratin, type I cytoskeletal 24
Names
CK-24
cytokeratin-24
keratin 24, type I
keratin-24
type I keratin-24

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012417.1 RefSeqGene

    Range
    5001..10760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_019016.2NP_061889.2  keratin, type I cytoskeletal 24

    See identical proteins and their annotated locations for NP_061889.2

    Status: REVIEWED

    Source sequence(s)
    AK000268, BC111968
    Consensus CDS
    CCDS11372.1
    UniProtKB/Swiss-Prot
    Q2M2I5
    Related
    ENSP00000264651, OTTHUMP00000164527, ENST00000264651, OTTHUMT00000257217
    Conserved Domains (1) summary
    pfam00038
    Location:140452
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p2 Primary Assembly

    Range
    40697991..40703750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524460.1XP_011522762.1  

    Conserved Domains (1) summary
    pfam00038
    Location:52349
    Filament; Intermediate filament protein
  2. XM_006721739.2XP_006721802.1  

    Conserved Domains (1) summary
    pfam00038
    Location:58354
    Filament; Intermediate filament protein

Alternate CHM1_1.1

Genomic

  1. NC_018928.2 Alternate CHM1_1.1

    Range
    39089584..39095343 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)