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mcm2 minichromosome maintenance complex component 2 [ Danio rerio (zebrafish) ]

Gene ID: 192338, updated on 8-May-2016
Official Symbol
mcm2provided by ZNC
Official Full Name
minichromosome maintenance complex component 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-020419-24
See related
Ensembl:ENSDARG00000102798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
cb737; chunp6905
Orthologs
Location:
chromosome: 22
Exon count:
16
Annotation release Status Assembly Chr Location
104 current GRCz10 (GCF_000002035.5) 22 NC_007133.6 (5604034..5624913, complement)
103 previous assembly Zv9 (GCF_000002035.4) Unplaced Scaffold NW_003336291.1 (11453..31970, complement)

Chromosome 22 - NC_007133.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101883897 Neighboring gene uncharacterized LOC101883755 Neighboring gene uncharacterized LOC103909523 Neighboring gene uncharacterized LOC101886604 Neighboring gene coiled-coil domain containing 51 Neighboring gene zgc:101000 Neighboring gene translation machinery associated 7 homolog

Markers

Homology

  • Homologs of the mcm2 gene: The mcm2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs from Annotation Pipeline: 184 organisms have orthologs with human gene mcm2

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA replication IEA
Inferred from Electronic Annotation
more info
 
DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 
retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
thymus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
MCM complex IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
DNA replication licensing factor MCM2
Names
MCM2 minichromosome maintenance deficient 2, mitotin
NP_775364.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173257.2NP_775364.2  DNA replication licensing factor MCM2

    Status: VALIDATED

    Source sequence(s)
    CU467843, EH588242
    UniProtKB/TrEMBL
    A0A0R4IF65
    Related
    ENSDARP00000133012, ENSDART00000159629
    Conserved Domains (4) summary
    cd00009
    Location:506646
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00350
    Location:279788
    MCM; minichromosome maintenance proteins
    pfam12619
    Location:57170
    MCM2_N; Mini-chromosome maintenance protein 2
    pfam14551
    Location:183298
    MCM_N; MCM N-terminal domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz10 Primary Assembly

Genomic

  1. NC_007133.6 Reference GRCz10 Primary Assembly

    Range
    5604034..5624913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)