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ZK550.2 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191349, updated on 23-Nov-2023

Summary

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Gene symbol
ZK550.2
Gene description
Major facilitator superfamily (MFS) profile domain-containing protein
Primary source
WormBase:WBGene00013996
Locus tag
CELE_ZK550.2
See related
AllianceGenome:WB:WBGene00013996
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in excretory cell and intestine. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Orthologous to human MFSD8 (major facilitator superfamily domain containing 8). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (17245584..17249750)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peptidase M3A/M3B catalytic domain-containing protein Neighboring gene ncRNA Neighboring gene HTH TFE/IIEalpha-type domain-containing protein Neighboring gene phytanoyl-CoA dioxygenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Major facilitator superfamily (MFS) profile domain-containing protein
NP_503058.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    17245584..17249750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070657.6 → NP_503058.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503058.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62511
    Conserved Domains (1) summary
    cd17326
    Location:38 → 480
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8
Nucleotide Protein
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