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Mapk11 mitogen-activated protein kinase 11 [ Mus musculus (house mouse) ]

Gene ID: 19094, updated on 8-May-2016
Official Symbol
Mapk11provided by MGI
Official Full Name
mitogen-activated protein kinase 11provided by MGI
Primary source
MGI:MGI:1338024
See related
Ensembl:ENSMUSG00000053137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P38b; Sapk2; p38-2; Prkm11; Sapk2b; p38beta; p38beta2
Orthologs
Location:
15; 15 E3
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (89142481..89149623, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (88972912..88980036, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene histone deacetylase 10 Neighboring gene mitogen-activated protein kinase 12 Neighboring gene predicted gene, 41379 Neighboring gene plexin B2 Neighboring gene microRNA 7118

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp586C1322

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding ISO
Inferred from Sequence Orthology
more info
 
MAP kinase activity ISO
Inferred from Sequence Orthology
more info
 
MAP kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity EXP
Inferred from Experiment
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
cellular response to virus ISO
Inferred from Sequence Orthology
more info
 
intracellular signal transduction ISO
Inferred from Sequence Orthology
more info
 
intracellular signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
negative regulation of cardiac muscle cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of interleukin-12 secretion ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
regulation of cardiac muscle cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to stress ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
mitogen-activated protein kinase 11
Names
MAP kinase 11
MAP kinase p38 beta
MAPK 11
mitogen activated protein kinase 11
mitogen-activated protein kinase p38 beta
protein kinase, mitogen activated kinase, 11, p38beta
NP_035291.4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011161.5NP_035291.4  mitogen-activated protein kinase 11

    See identical proteins and their annotated locations for NP_035291.4

    Status: VALIDATED

    Source sequence(s)
    AI480540, BC092526
    Consensus CDS
    CCDS27741.1
    UniProtKB/Swiss-Prot
    Q9WUI1
    Related
    ENSMUSP00000086204, ENSMUST00000088823
    Conserved Domains (2) summary
    smart00220
    Location:27308
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8350
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    89142481..89149623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245521.1XP_011243823.1  

    Conserved Domains (2) summary
    smart00220
    Location:5283
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:5325
    PKc_like; Protein Kinases, catalytic domain
  2. XM_006520630.2XP_006520693.1  

    Conserved Domains (2) summary
    smart00220
    Location:27232
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8227
    PKc_like; Protein Kinases, catalytic domain

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    91271050..91278706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)