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    Pou5f1 POU domain, class 5, transcription factor 1 [ Mus musculus ]

    Gene ID: 18999, updated on 13-May-2012

    Summary

    Official Symbol
    Pou5f1provided by MGI
    Official Full Name
    POU domain, class 5, transcription factor 1provided by MGI
    Primary source
    MGI:101893
    See related
    Ensembl:ENSMUSG00000024406; Vega:OTTMUSG00000037235
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Oct3; Oct4; Otf3; Otf4; NF-A3; Oct-3; Oct-4; Otf-3; Otf-4; Otf3g; Oct3/4; Oct-3/4; Otf3-rs7

    Genomic context

    Location :
    17 B1; 17 19.23 cM
    Sequence :
    Chromosome: 17; NC_000083.6 (35506032..35510777)
    See Pou5f1 in Epigenomics, MapViewer

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene archain 1 pseudogene Neighboring gene histocompatibility 2, Q region locus 10 Neighboring gene predicted gene, 19553 Neighboring gene transcription factor 19 Neighboring gene coiled-coil alpha-helical rod protein 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    CAA36682.1 CAA36682.1 Pou5f1    BIND  PubMed OCT4 interacts with itself. 
    NP_038661.1 AF132745.1     BIND  PubMed Oct4 binds to Sox2 HSI element. 
    NP_038661.1 AF132745.1     BIND  PubMed Oct4 binds to POU site1. 
    BioGRID:202313 BioGRID:222642 0610010K14Rik    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:231423 2210018M11Rik    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:212044 2810474O19Rik    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207849 Acin1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207995 Actl6a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207953 Akap8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207908 Amotl2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207941 Arid3b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:211447 Asf1a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198233 Atf2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:220337 Brwd1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:222491 Cabin1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:213636 Cad    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198624 Cdk1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198693 Chd1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:229802 Chd3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:223700 Chd4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:234678 Chd5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198873 Creb1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198961 Ctbp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198962 Ctbp2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:211163 Cubn    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:215452 Cul4b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199074 Ddb1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199088 Dhx9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:200446 Dnaja1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199261 Dnmt3a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207659 Dnmt3l    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202862 Dpf2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199436 Emd    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:217577 Ep400    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204938 Esrrb    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:199551 Ewsr1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:216509 Foxp4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199743 Frg1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:231518 Gatad2a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:230858 Gatad2b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:200248 Hcfc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:241423 Hdac1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:200260 Hdac2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:200271 Hells    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:200309 Hira    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:235070 Hist1h3e    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:236473 Hist1h4b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:238405 Hist3h2bb-ps    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:200358 Hnrnpab    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:200360 Hnrnpl    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:206185 Hnrnpu    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204945 Ifi202b    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:212438 Ilf2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:212678 Ino80    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:221360 Kdm1a    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:200966 Klf4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198396 Klf5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201007 Kpna2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201008 Kpna3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:238004 L1td1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201165 Lig3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201324 Matr3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201332 Mbd3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:205889 Mga    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201427 Mitf    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201525 Msh2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201528 Msh6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:228045 Mta1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:204807 Mta2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:228046 Mta3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:229849 Myst2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:211748 Nacc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:215050 Nanog    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex 
    BioGRID:202313 BioGRID:201706 Ncl    BioGRID  PubMed Affinity Capture-Luminescence 
    BioGRID:202313 BioGRID:231624 Nfrkb    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:201762 Nfyc    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198035 Nr0b1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:201876 Nudc    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:223870 Ogt    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202006 P4ha1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:197998 Parp1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:199382 Phc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:234652 Phf17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202265 Pml    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202313 Pou5f1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:206176 Ppp2r1a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202423 Psmb6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:232827 Rbbp7    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:207870 Rbm14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202832 Rbpj    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:222597 Rcor2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202873 Rfx2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:206234 Rif1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:202919 Rnf2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:212778 Rpa1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:212756 Rpa3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207918 Rybp    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:207998 Sae1    BioGRID  PubMed Biochemical Activity 
    BioGRID:202313 BioGRID:208384 Sall1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:203420 Sall3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:221236 Sall4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:203336 Smarca4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:220300 Smarca5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:203338 Smarcc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204874 Smc1a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:203402 Sox15    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:202313 BioGRID:203406 Sox2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:203414 Sp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:203512 Ssrp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204420 Sumo1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:202313 BioGRID:227853 Supt16h    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:219895 Tfcp2l1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:229078 Tfe3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204016 Tfeb    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204276 Top2a    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204196 Trim24    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:220448 Trim33    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:221510 Trrap    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:216447 Ttf2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:206169 Uba2    BioGRID  PubMed Biochemical Activity 
    BioGRID:202313 BioGRID:204408 Ube2i    BioGRID  PubMed Biochemical Activity 
    BioGRID:202313 BioGRID:236097 Ubn2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204421 Ubp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:228326 Wdr5    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:202313 BioGRID:211793 Wwp2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:202313 BioGRID:204607 Xrcc1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204608 Xrcc5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:199785 Xrcc6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:230814 Zbtb10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:238180 Zbtb2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:214963 Zbtb43    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:214189 Zcchc8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:198230 Zfhx3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:203516 Zfp143    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-localization 
    BioGRID:202313 BioGRID:230795 Zfp217    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:213739 Zfp219    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204664 Zfp42    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:232406 Zfp462    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:221569 Zfp513    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:204695 Zic2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:217903 Zmym2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:202313 BioGRID:577634 Zscan4b    BioGRID  PubMed Affinity Capture-MS 

    General gene information

    Markers

    Homology

    Pathways from BioSystems

    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...
    • Wnt Signaling Pathway and Pluripotency, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway and Pluripotency, organism-specific biosystemThis pathway was adapted from several resources and is designed to provide a theoretical frame-work for examining Wnt signaling and interacting components in the context of embryonic stem-cell pluri...

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    miRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding RNA polymerase II transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific DNA binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
     
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    BMP signaling pathway involved in heart induction ISO
    Inferred from Sequence Orthology
    more info
     
    cardiac cell fate determination ISO
    Inferred from Sequence Orthology
    more info
     
    cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell fate commitment involved in formation of primary germ layers ISO
    Inferred from Sequence Orthology
    more info
     
    ectodermal cell fate commitment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endodermal cell fate commitment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endodermal cell fate specification ISO
    Inferred from Sequence Orthology
    more info
     
    germ-line stem cell maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mRNA transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mesodermal cell fate commitment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of calcium ion-dependent exocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of gene silencing by miRNA ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription, DNA-dependent IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of SMAD protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of catenin import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-dependent IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of heart induction by regulation of canonical Wnt receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of methylation-dependent chromatin silencing ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-dependent IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-dependent ISO
    Inferred from Sequence Orthology
    more info
     
    response to chemical stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to retinoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    somatic stem cell maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    stem cell differentiation IDA
    Inferred from Direct Assay
    more info
     
    stem cell maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription, DNA-dependent IEA
    Inferred from Electronic Annotation
    more info
     
    trophectodermal cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IC
    Inferred by Curator
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    soluble fraction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptional repressor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    POU domain, class 5, transcription factor 1
    Names
    POU domain, class 5, transcription factor 1
    octamer-binding protein 3
    octamer-binding protein 4
    octamer-binding transcription factor 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252452.1NP_001239381.1  POU domain, class 5, transcription factor 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream, in-frame start codon, compared to variant 1. the encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AB375270, AW536651, BY390845
      Conserved Domains (2) summary
      cd00086
      Location:93151
      Blast Score: 148
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cl02582
      Location:374
      Blast Score: 344
      Pou; Pou domain - N-terminal to homeobox domain
    2. NM_013633.3NP_038661.2  POU domain, class 5, transcription factor 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK145321, BY390845, CR974473
      Consensus CDS
      CCDS37600.1
      UniProtKB/Swiss-Prot
      P20263
      Related
      ENSMUSP00000025271, OTTMUSP00000053597, ENSMUST00000025271, OTTMUST00000096009
      Conserved Domains (2) summary
      cd00086
      Location:224282
      Blast Score: 155
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cl02582
      Location:131205
      Blast Score: 353
      Pou; Pou domain - N-terminal to homeobox domain

    RefSeqs of Annotated Genomes: Build 38.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38 129X1/SvJ

    Genomic

    1. NT_039662.3 Reference GRCm38 129X1/SvJ

      Range
      1824981..1829725
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38 C57BL/6J

      Range
      35506032..35510777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38 NOD/MrkTac

    Genomic

    1. NT_187027.1 Reference GRCm38 NOD/MrkTac

      Range
      1819229..1823763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000039.1 Alternate Mm_Celera

      Range
      39020977..39025724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AC087216.1 (117182..121899) None 129/SvJ
    genomic AJ297528.1 None
    genomic CH466559.1 EDL23215.1 mixed
    genomic CR974473.23 (71242..75978) None
    genomic S58422.1 AAB19896.1
    genomic S58423.1 AAB19896.1
    genomic S58424.1 AAB19896.1
    genomic S58425.1 AAB19896.1
    genomic S58426.1 AAB19896.1
    genomic S62878.1 None
    genomic S62880.1 None
    genomic S68053.1 None
    genomic S78374.1 None
    genomic S78376.1 None
    genomic S78378.1 None
    mRNA AB221654.1 None
    mRNA AB375269.1 BAG84134.1
    mRNA AB375270.1 None
    mRNA AB375271.1 BAL14699.1
    mRNA AB375272.1 BAG84135.1
    mRNA AB375273.1 BAG84136.1
    mRNA AB375274.1 BAG84137.1
    mRNA AB375275.1 None
    mRNA AB375277.1 BAG84138.1
    mRNA AB375278.1 BAG84139.1
    mRNA AK145321.1 None C57BL/6J
    mRNA AW536651.1 None C57BL/6J
    mRNA BC068268.1 AAH68268.1 C57BL/6J
    mRNA BY390845.1 None C57BL/6J
    mRNA CJ059769.1 None C57BL/6J
    mRNA M34381.1 AAA39844.1
    mRNA X52437.1 CAA36682.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20263.1 GenPept UniProtKB/Swiss-Prot:P20263

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