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T04F3.4 EF-hand domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188064, updated on 7-Sep-2023

Summary

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Gene symbol
T04F3.4
Gene description
EF-hand domain-containing protein
Primary source
WormBase:WBGene00011439
Locus tag
CELE_T04F3.4
See related
AllianceGenome:WB:WBGene00011439
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Orthologous to human MCFD2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (11761893..11763049, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene EF-hand domain-containing protein Neighboring gene Putative syntaxin-5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
EF-hand domain-containing protein
NP_505966.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11761893..11763049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073565.6 → NP_505966.1  EF-hand domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505966.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22159
    Conserved Domains (2) summary
    pfam13499
    Location:58 → 125
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:58 → 125
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

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