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Pkig protein kinase inhibitor, gamma [ Mus musculus (house mouse) ]

Gene ID: 18769, updated on 8-May-2016
Official Symbol
Pkigprovided by MGI
Official Full Name
protein kinase inhibitor, gammaprovided by MGI
Primary source
MGI:MGI:1343086
See related
Ensembl:ENSMUSG00000035268 Vega:OTTMUSG00000001148
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PKIgamma
Orthologs
Location:
2 H3; 2 84.4 cM
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (163658386..163726158)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (163484122..163551894)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene tocopherol (alpha) transfer protein-like Neighboring gene serine incorporator 3 Neighboring gene RIKEN cDNA 0610039K10 gene Neighboring gene uncharacterized LOC102639518 Neighboring gene adenosine deaminase Neighboring gene WNT1 inducible signaling pathway protein 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cAMP-dependent protein kinase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
cAMP-dependent protein kinase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
protein kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
cAMP-dependent protein kinase inhibitor gamma

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039390.2NP_001034479.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

    See identical proteins and their annotated locations for NP_001034479.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AK164716, BY283174, BY617655, CJ051558
    Consensus CDS
    CCDS17014.1
    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000096704, OTTMUSP00000001089, ENSMUST00000099105, OTTMUST00000002240
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor
  2. NM_001039391.2NP_001034480.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

    See identical proteins and their annotated locations for NP_001034480.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AK164716, BY343638, BY617655, CJ051558
    Consensus CDS
    CCDS17014.1
    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000068344, OTTMUSP00000001087, ENSMUST00000064703, OTTMUST00000002238
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor
  3. NM_001164053.1NP_001157525.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

    See identical proteins and their annotated locations for NP_001157525.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AK164716, BY240874, BY266193, BY617655
    Consensus CDS
    CCDS17014.1
    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000120145, OTTMUSP00000045306, ENSMUST00000126182, OTTMUST00000038604
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor
  4. NM_001164055.1NP_001157527.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

    See identical proteins and their annotated locations for NP_001157527.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AL591490
    Consensus CDS
    CCDS17014.1
    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000126223, ENSMUST00000164399
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor
  5. NM_001277096.1NP_001264025.1  cAMP-dependent protein kinase inhibitor gamma isoform 2

    See identical proteins and their annotated locations for NP_001264025.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate in-frame splice site, compared to variant 4. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AL591490
    Conserved Domains (1) summary
    pfam02827
    Location:274
    PKI; cAMP-dependent protein kinase inhibitor
  6. NM_011106.2NP_035236.1  cAMP-dependent protein kinase inhibitor gamma isoform 1

    See identical proteins and their annotated locations for NP_035236.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, compared to variant 4. Variants 1, 2, 3, 4, and 5 encode the same isoform (1).
    Source sequence(s)
    AV342749, U97170, W75470
    Consensus CDS
    CCDS17014.1
    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000105027, OTTMUSP00000001088, ENSMUST00000109400, OTTMUST00000002239
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    163658386..163726158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498926.2XP_006498989.1  

    See identical proteins and their annotated locations for XP_006498989.1

    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor
  2. XM_006498927.1XP_006498990.1  

    See identical proteins and their annotated locations for XP_006498990.1

    UniProtKB/Swiss-Prot
    O70139
    UniProtKB/TrEMBL
    Q3TP50
    Related
    ENSMUSP00000120355, OTTMUSP00000045305, ENSMUST00000131228, OTTMUST00000084147
    Conserved Domains (1) summary
    pfam02827
    Location:275
    PKI; cAMP-dependent protein kinase inhibitor

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    169601971..169669883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)