Format

Send to:

Choose Destination

Piga phosphatidylinositol glycan anchor biosynthesis, class A [ Mus musculus (house mouse) ]

Gene ID: 18700, updated on 8-May-2016
Official Symbol
Pigaprovided by MGI
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class Aprovided by MGI
Primary source
MGI:MGI:99461
See related
Ensembl:ENSMUSG00000031381 Vega:OTTMUSG00000019508
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pig-a; AI194334
Orthologs
Location:
X 76.49 cM; X F3-F4
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (164419680..164433916)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (160857719..160871847)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene BMX non-receptor tyrosine kinase Neighboring gene predicted gene, 19251 Neighboring gene pirin Neighboring gene c-fos induced growth factor Neighboring gene ankyrin repeat and SOCS box-containing 11 Neighboring gene ankyrin repeat and SOCS box-containing 9

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring glycosyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
GPI anchor biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
Names
glcNAc-PI synthesis protein
phosphatidylinositol glycan, class A
phosphatidylinositol-glycan biosynthesis class A protein
phosphatidylinositolglycan class A
NP_035211.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011081.2NP_035211.2  N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

    See identical proteins and their annotated locations for NP_035211.2

    Status: VALIDATED

    Source sequence(s)
    AK032283, AK039802, BB707289, BB771632, BY270710
    Consensus CDS
    CCDS30522.1
    UniProtKB/Swiss-Prot
    Q64323
    UniProtKB/TrEMBL
    A2AIH5
    Related
    ENSMUSP00000033754, OTTMUSP00000021037, ENSMUST00000033754, OTTMUST00000046585
    Conserved Domains (2) summary
    cd03796
    Location:34433
    GT1_PIG-A_like; This family is most closely related to the GT1 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate ...
    COG0438
    Location:34405
    RfaB; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    164419680..164433916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528758.2XP_006528821.1  

    See identical proteins and their annotated locations for XP_006528821.1

    UniProtKB/TrEMBL
    Q3TB52
    Conserved Domains (2) summary
    COG0438
    Location:189
    RfaB; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
    cl10013
    Location:1117
    Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
  2. XM_011247793.1XP_011246095.1  

    Related
    ENSMUSP00000146731, OTTMUSP00000075504, ENSMUST00000208697, OTTMUST00000144922
    Conserved Domains (2) summary
    COG0438
    Location:9180
    RfaB; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
    cl10013
    Location:13208
    Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    147635146..147649303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)