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ilkp-1 PPM-type phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 185220, updated on 23-Nov-2023

Summary

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Gene symbol
ilkp-1
Gene description
PPM-type phosphatase domain-containing protein
Primary source
WormBase:WBGene00009354
Locus tag
CELE_F33A8.6
See related
AllianceGenome:WB:WBGene00009354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be active in cytosol and nucleus. Orthologous to human ILKAP (ILK associated serine/threonine phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (11050255..11058124)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene CTCHY-type domain-containing protein Neighboring gene Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Adapter protein unc-53;Calponin-homology (CH) domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
PPM-type phosphatase domain-containing protein
NP_496370.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11050255..11058124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063969.3 → NP_496370.2  PPM-type phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496370.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EDI3
    Conserved Domains (1) summary
    cd00143
    Location:34 → 316
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
Nucleotide Protein
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