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P2ry2 purinergic receptor P2Y, G-protein coupled 2 [ Mus musculus (house mouse) ]

Gene ID: 18442, updated on 28-May-2016
Official Symbol
P2ry2provided by MGI
Official Full Name
purinergic receptor P2Y, G-protein coupled 2provided by MGI
Primary source
MGI:MGI:105107
See related
Ensembl:ENSMUSG00000032860 Vega:OTTMUSG00000060008
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P2U1; P2Y2
Orthologs
Location:
7; 7 F1
Exon count:
3
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (100996568..101012053, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (108145086..108160505, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor (GEF) 17 Neighboring gene microRNA 3102 Neighboring gene pyrimidinergic receptor P2Y, G-protein coupled, 6 Neighboring gene ribosomal protein S29 pseudogene Neighboring gene FCH and double SH3 domains 2 Neighboring gene ribosomal protein L27 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
A1 adenosine receptor binding ISO
Inferred from Sequence Orthology
more info
 
ATP binding ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled purinergic nucleotide receptor activity IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
UTP-activated nucleotide receptor activity ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of ossification ISO
Inferred from Sequence Orthology
more info
 
phospholipase C-activating G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation of chemokine production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mucus secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of penile erection ISO
Inferred from Sequence Orthology
more info
 
positive regulation of prostaglandin secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of smooth muscle cell migration ISO
Inferred from Sequence Orthology
more info
 
regulation of vasodilation ISO
Inferred from Sequence Orthology
more info
 
sensory perception of pain ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with early endosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with lysosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
P2Y purinoceptor 2
Names
ATP receptor
P2U purinoceptor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302346.1NP_001289275.1  P2Y purinoceptor 2

    See identical proteins and their annotated locations for NP_001289275.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC151414, AK005013
    Consensus CDS
    CCDS21508.1
    UniProtKB/Swiss-Prot
    P35383
    UniProtKB/TrEMBL
    A0A0R4J289
    Related
    ENSMUSP00000146352, OTTMUSP00000076486, ENSMUST00000207916, OTTMUST00000147000
    Conserved Domains (1) summary
    pfam00001
    Location:56306
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_001302347.1NP_001289276.1  P2Y purinoceptor 2

    See identical proteins and their annotated locations for NP_001289276.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC151414, AK005013, AK017378
    Consensus CDS
    CCDS21508.1
    UniProtKB/Swiss-Prot
    P35383
    UniProtKB/TrEMBL
    A0A0R4J289
    Related
    ENSMUSP00000137152, OTTMUSP00000076487, ENSMUST00000178340, OTTMUST00000147001
    Conserved Domains (1) summary
    pfam00001
    Location:56306
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. NM_008773.4NP_032799.2  P2Y purinoceptor 2

    See identical proteins and their annotated locations for NP_032799.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC151414, AK005013, AK017378
    Consensus CDS
    CCDS21508.1
    UniProtKB/Swiss-Prot
    P35383
    UniProtKB/TrEMBL
    A0A0R4J289
    Related
    ENSMUSP00000036765, OTTMUSP00000076427, ENSMUST00000037540, OTTMUST00000146919
    Conserved Domains (1) summary
    pfam00001
    Location:56306
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    100996568..101012053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    101348335..101364047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)