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P2ry1 purinergic receptor P2Y, G-protein coupled 1 [ Mus musculus (house mouse) ]

Gene ID: 18441, updated on 15-May-2016
Official Symbol
P2ry1provided by MGI
Official Full Name
purinergic receptor P2Y, G-protein coupled 1provided by MGI
Primary source
MGI:MGI:105049
See related
Ensembl:ENSMUSG00000027765 Vega:OTTMUSG00000051935
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P2Y1
Orthologs
Location:
3; 3 D
Exon count:
2
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (61002785..61008982)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (60806717..60812901)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 37035 Neighboring gene predicted gene, 38326 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene Neighboring gene splicing factor, arginine/serine-rich 13A-like Neighboring gene RAP2B, member of RAS oncogene family

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
A1 adenosine receptor binding ISO
Inferred from Sequence Orthology
more info
 
ADP binding ISO
Inferred from Sequence Orthology
more info
 
ADP-activated adenosine receptor activity ISO
Inferred from Sequence Orthology
more info
 
ATP binding ISO
Inferred from Sequence Orthology
more info
 
ATP-activated adenosine receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled purinergic nucleotide receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled purinergic nucleotide receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
adenosine receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
cellular response to organic cyclic compound IDA
Inferred from Direct Assay
more info
PubMed 
eating behavior ISO
Inferred from Sequence Orthology
more info
 
glial cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of binding ISO
Inferred from Sequence Orthology
more info
 
negative regulation of norepinephrine secretion ISO
Inferred from Sequence Orthology
more info
 
phospholipase C-activating G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
platelet activation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of hormone secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of inositol trisphosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ion transport IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of penile erection ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
regulation of receptor activity ISO
Inferred from Sequence Orthology
more info
 
regulation of vasodilation ISO
Inferred from Sequence Orthology
more info
 
relaxation of muscle IEA
Inferred from Electronic Annotation
more info
 
response to mechanical stimulus ISO
Inferred from Sequence Orthology
more info
 
sensory perception of pain ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
signal transduction involved in regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cell body ISO
Inferred from Sequence Orthology
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion ISO
Inferred from Sequence Orthology
more info
 
neuronal postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
P2Y purinoceptor 1
Names
ATP receptor
P2Y1 receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282016.1NP_001268945.1  P2Y purinoceptor 1

    See identical proteins and their annotated locations for NP_001268945.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK030759, AK033660, BY780693
    Consensus CDS
    CCDS17377.1
    UniProtKB/Swiss-Prot
    P49650
    UniProtKB/TrEMBL
    Q544J5, Q8BMJ5
    Related
    ENSMUSP00000142006, OTTMUSP00000070028, ENSMUST00000193201, OTTMUST00000130724
    Conserved Domains (1) summary
    pfam00001
    Location:74324
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_008772.5NP_032798.1  P2Y purinoceptor 1

    See identical proteins and their annotated locations for NP_032798.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK030759, AK033660, AK036611, BY780693
    Consensus CDS
    CCDS17377.1
    UniProtKB/Swiss-Prot
    P49650
    UniProtKB/TrEMBL
    Q544J5, Q8BMJ5
    Related
    ENSMUSP00000029331, OTTMUSP00000070027, ENSMUST00000029331, OTTMUST00000130723
    Conserved Domains (1) summary
    pfam00001
    Location:74324
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    61002785..61008982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    60703945..60710144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)