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Gpr143 G protein-coupled receptor 143 [ Mus musculus (house mouse) ]

Gene ID: 18241, updated on 28-May-2016
Official Symbol
Gpr143provided by MGI
Official Full Name
G protein-coupled receptor 143provided by MGI
Primary source
MGI:MGI:107193
See related
Ensembl:ENSMUSG00000025333 Vega:OTTMUSG00000019341
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oa1
Orthologs
Location:
X 68.46 cM; X F2-F3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (152781921..152808651)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (149216464..149243189)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene RAB7, member RAS oncogene family pseudogene Neighboring gene shroom family member 2 Neighboring gene phosphoglycerate mutase 2 pseudogene Neighboring gene ribosomal protein L7A, pseudogene 12 Neighboring gene ribosomal protein S7 pseudogene Neighboring gene ubiquitin specific protease 51

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
L-DOPA binding ISO
Inferred from Sequence Orthology
more info
 
L-DOPA receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
L-DOPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
dopamine binding ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
tyrosine binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
calcium-mediated signaling using intracellular calcium source ISO
Inferred from Sequence Orthology
more info
 
melanosome localization ISO
Inferred from Sequence Orthology
more info
 
melanosome organization ISO
Inferred from Sequence Orthology
more info
 
melanosome transport ISO
Inferred from Sequence Orthology
more info
 
phosphatidylinositol-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
regulation of melanosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of melanosome transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
lysosome IEA
Inferred from Electronic Annotation
more info
 
melanosome ISO
Inferred from Sequence Orthology
more info
 
melanosome membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
G-protein coupled receptor 143
Names
MOA1
homolog of human ocular albinism 1 (Nettleship-Falls)
ocular albinism type 1 protein homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010951.3NP_035081.3  G-protein coupled receptor 143

    See identical proteins and their annotated locations for NP_035081.3

    Status: VALIDATED

    Source sequence(s)
    BB762363, BC119384, CJ131873
    Consensus CDS
    CCDS30476.1
    UniProtKB/Swiss-Prot
    P70259
    UniProtKB/TrEMBL
    Q549B6
    Related
    ENSMUSP00000026383, OTTMUSP00000020865, ENSMUST00000026383, OTTMUST00000046178
    Conserved Domains (1) summary
    pfam02101
    Location:1405
    Ocular_alb; Ocular albinism type 1 protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    152781921..152808651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528746.1XP_006528809.1  

    Conserved Domains (1) summary
    cl21587
    Location:1246
    7tm_2; 7 transmembrane receptor (Secretin family)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    136442756..136469491 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)