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Ntsr2 neurotensin receptor 2 [ Mus musculus (house mouse) ]

Gene ID: 18217, updated on 28-May-2016
Official Symbol
Ntsr2provided by MGI
Official Full Name
neurotensin receptor 2provided by MGI
Primary source
MGI:MGI:108018
See related
Ensembl:ENSMUSG00000020591
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NT2R; NTRL
Orthologs
Location:
12 A1.1; 12 7.98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 12 NC_000078.6 (16653452..16660236)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (16660276..16667042)

Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36320 Neighboring gene lipin 1 Neighboring gene gene regulated by estrogen in breast cancer protein Neighboring gene E2F transcription factor 6

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled neurotensin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
phospholipase C-activating G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
regulation of membrane potential IDA
Inferred from Direct Assay
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
dendritic shaft ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
perikaryon ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
neurotensin receptor type 2
Names
NT-R-2
NTR2
low affinity neurotensin receptor
low-affinity levocabastine-sensitive neurotensin receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008747.2NP_032773.2  neurotensin receptor type 2

    See identical proteins and their annotated locations for NP_032773.2

    Status: VALIDATED

    Source sequence(s)
    AK158943, BB264011
    Consensus CDS
    CCDS36407.1
    UniProtKB/Swiss-Prot
    P70310
    Related
    ENSMUSP00000106693, ENSMUST00000111064
    Conserved Domains (1) summary
    pfam00001
    Location:87358
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000078.6 Reference GRCm38.p3 C57BL/6J

    Range
    16653452..16660236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515011.2XP_006515074.1  

    Conserved Domains (1) summary
    pfam00001
    Location:87233
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. XM_006515012.2XP_006515075.1  

    Conserved Domains (1) summary
    pfam00001
    Location:87233
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. XM_006515013.2XP_006515076.1  

    Conserved Domains (1) summary
    pfam00001
    Location:87233
    7tm_1; 7 transmembrane receptor (rhodopsin family)

Alternate Mm_Celera

Genomic

  1. AC_000034.1 Alternate Mm_Celera

    Range
    16974035..16980752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)