Format

Send to:

Choose Destination

Nid2 nidogen 2 [ Mus musculus (house mouse) ]

Gene ID: 18074, updated on 28-May-2016
Official Symbol
Nid2provided by MGI
Official Full Name
nidogen 2provided by MGI
Primary source
MGI:MGI:1298229
See related
Ensembl:ENSMUSG00000021806
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly111; NID-2; AW547149; nidogen-2; entactin-2
Orthologs
Location:
14; 14 A3
Exon count:
21
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 14 NC_000080.6 (19751257..19811787)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (20570479..20631009)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene 17030 Neighboring gene prostaglandin D receptor pseudogene Neighboring gene predicted gene, 29899 Neighboring gene predicted gene, 41103 Neighboring gene RIKEN cDNA 2700060E02 gene Neighboring gene DNA segment, Chr 14, ERATO Doi 670, expressed Neighboring gene guanine nucleotide binding protein (G protein), gamma 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell-matrix adhesion IDA
Inferred from Direct Assay
more info
PubMed 
cell-matrix adhesion IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
basement membrane IDA
Inferred from Direct Assay
more info
PubMed 
basement membrane IPI
Inferred from Physical Interaction
more info
PubMed 
basement membrane ISO
Inferred from Sequence Orthology
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular matrix IDA
Inferred from Direct Assay
more info
PubMed 
extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
proteinaceous extracellular matrix IDA
Inferred from Direct Assay
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008695.2NP_032721.2  nidogen-2 precursor

    See identical proteins and their annotated locations for NP_032721.2

    Status: VALIDATED

    Source sequence(s)
    AK052839, AK164258, AY074820, BY143483
    Consensus CDS
    CCDS36813.1
    UniProtKB/Swiss-Prot
    O88322
    UniProtKB/TrEMBL
    Q3TPN0, Q8C6Z2, Q8R5G0
    Related
    ENSMUSP00000022340, ENSMUST00000022340
    Conserved Domains (6) summary
    smart00135
    Location:12061248
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00539
    Location:108275
    NIDO; Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins
    cd00054
    Location:915953
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00191
    Location:10471112
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    cd00255
    Location:550774
    nidG2; Nidogen, G2 domain; Nidogen is an important component of the basement membrane, an extracellular sheet-like matrix. Nidogen is a multifunctional protein that interacts with many other basement membrane proteins, like collagen, perlecan, lamin, and has a ...
    pfam12947
    Location:786822
    EGF_3; EGF domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p3 C57BL/6J

    Range
    19751257..19811787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000036.1 Alternate Mm_Celera

    Range
    16134631..16194784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)