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    Nat3 N-acetyltransferase 3 [ Mus musculus (house mouse) ]

    Gene ID: 17962, updated on 11-May-2013
    Official Symbol
    Nat3provided by MGI
    Official Full Name
    N-acetyltransferase 3provided by MGI
    Primary source
    MGI:102537
    See related
    Ensembl:ENSMUSG00000056426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Location :
    8 B3.3; 8 33.39 cM
    Sequence :
    Chromosome: 8; NC_000074.6 (67523854..67548627)
    See Nat3 in Epigenomics, MapViewer

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene Tu translation elongation factor pseudogene Neighboring gene N-acetyltransferase 2 (arylamine N-acetyltransferase) Neighboring gene pleckstrin and Sec7 domain containing 3 Neighboring gene SH2 domain containing 4A Neighboring gene upstream binding transcription factor, RNA polymerase I-like 1 pseudogene

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    3. Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse. Sugamori KS, et al. Drug Metab Dispos, 2007 Jul. PMID 17403913.
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072.

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Generated Nat3 knockout mouse, showing that Nat3 is unlikely to play a significant role in the N-acetylation of arylamines either in wild-type mice or in mice lacking Nat1 and Nat2 activities.
      Title: Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse.
    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    L-amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    arylamine N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    L-amino acid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    amino acid transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Preferred Names
    arylamine N-acetyltransferase 3
    Names
    arylamine N-acetyltransferase 3
    NAT-3
    arylamide acetylase 3
    N-acetyltransferase type 3
    NP_032700.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008674.2 → NP_032700.1  arylamine N-acetyltransferase 3

      Status: VALIDATED

      Source sequence(s)
      AK077364
      Consensus CDS
      CCDS22339.1
      UniProtKB/Swiss-Prot
      P50296
      UniProtKB/TrEMBL
      Q546K5
      Related
      ENSMUSP00000069359, ENSMUST00000070514
      Conserved Domains (1) summary
      pfam00797
      Location:20 – 280
      Blast Score: 788
      Acetyltransf_2; N-acetyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p1 C57BL/6J

      Range
      67523854..67548627
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000030.1 Alternate Mm_Celera

      Range
      70077424..70102253
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01071728.1 (2240..16003) None
    genomic AAHY01071729.1 None
    genomic AC141868.4 (112673..137446) None
    genomic AJ314661.1 CAC85420.1 129/Ola
    genomic AJ314662.1 CAC85421.1 CBA
    genomic AJ314663.1 CAC85422.1 po(oxford)
    genomic AJ314664.1 CAC85423.1 TO
    genomic AJ314665.1 CAC85424.1
    genomic CH466569.1 EDL28712.1 mixed
    genomic X72959.1 CAA51461.1 BALB/c
    mRNA AK077364.1 BAC36769.1 C57BL/6J
    other-genetic BC140232.1 AAI40233.1
    other-genetic BC141615.1 AAI41616.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50296.1 GenPept UniProtKB/Swiss-Prot:P50296

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

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