Format

Send to:

Choose Destination

Myo10 myosin X [ Mus musculus (house mouse) ]

Gene ID: 17909, updated on 28-May-2016
Official Symbol
Myo10provided by MGI
Official Full Name
myosin Xprovided by MGI
Primary source
MGI:MGI:107716
See related
Ensembl:ENSMUSG00000022272 Vega:OTTMUSG00000020342
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AW048724; mKIAA0799; D15Ertd600e
Orthologs
Location:
15 C; 15 9.36 cM
Exon count:
43
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (25622550..25813673)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (25552305..25743426)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene brain abundant, membrane attached signal protein 1 Neighboring gene predicted gene 5468 Neighboring gene PCNA-associated factor pseudogene Neighboring gene family with sequence similarity 134, member B Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene 15_175.1 Neighboring gene microRNA 7212

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1) 
  • Gene trapped (1) 
  • Targeted (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
actin binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding ISO
Inferred from Sequence Orthology
more info
 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
motor activity ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
spectrin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
cell motility IC
Inferred by Curator
more info
PubMed 
positive regulation of cell-cell adhesion IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
regulation of filopodium assembly ISO
Inferred from Sequence Orthology
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
filopodium IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
myosin complex IEA
Inferred from Electronic Annotation
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
ruffle ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
unconventional myosin-X
Names
myosin-X
unconventional myosin-10
unconventionnal myosin-X

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019472.2NP_062345.2  unconventional myosin-X

    See identical proteins and their annotated locations for NP_062345.2

    Status: VALIDATED

    Source sequence(s)
    AK028552, AK089482, AK122371
    Consensus CDS
    CCDS37049.1
    UniProtKB/Swiss-Prot
    F8VQB6
    UniProtKB/TrEMBL
    Q80TR9
    Related
    ENSMUSP00000106087, OTTMUSP00000022066, ENSMUST00000110457, OTTMUST00000048259
    Conserved Domains (12) summary
    smart00015
    Location:741763
    IQ; Calmodulin-binding motif
    smart00139
    Location:15531699
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00242
    Location:58739
    MYSc; Myosin. Large ATPases
    smart00295
    Location:17081962
    B41; Band 4.1 homologues
    cd13202
    Location:19582046
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:12191320
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:13851510
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14473
    Location:18101954
    FERM_B-lobe; FERM domain B-lobe
    cd14873
    Location:77727
    MYSc_Myo10; class X myosin, motor domain
    cl00155
    Location:17051750
    UBQ; Ubiquitin-like proteins
    cl17171
    Location:11851227
    PH-like; Pleckstrin homology-like domain
    cl21485
    Location:857947
    OmpH; Outer membrane protein (OmpH-like)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    25622550..25813673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520025.2XP_006520088.1  

    UniProtKB/Swiss-Prot
    F8VQB6
    Conserved Domains (11) summary
    smart00015
    Location:98120
    IQ; Calmodulin-binding motif
    smart00139
    Location:9101056
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:10651319
    B41; Band 4.1 homologues
    cd13202
    Location:13151403
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:576677
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:742867
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14473
    Location:11671311
    FERM_B-lobe; FERM domain B-lobe
    cl00155
    Location:10621107
    UBQ; Ubiquitin-like proteins
    cl17171
    Location:542584
    PH-like; Pleckstrin homology-like domain
    cl21485
    Location:214304
    OmpH; Outer membrane protein (OmpH-like)
    cl22853
    Location:184
    Motor_domain; Myosin and Kinesin motor domain.
  2. XM_006520027.2XP_006520090.1  

    UniProtKB/TrEMBL
    E9Q5G1
    Related
    ENSMUSP00000022882, OTTMUSP00000022073, ENSMUST00000022882, OTTMUST00000048267
    Conserved Domains (9) summary
    smart00139
    Location:807953
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:9621216
    B41; Band 4.1 homologues
    cd13202
    Location:12121300
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:473574
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:639764
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14473
    Location:10641208
    FERM_B-lobe; FERM domain B-lobe
    cl00155
    Location:9591004
    UBQ; Ubiquitin-like proteins
    cl17171
    Location:439481
    PH-like; Pleckstrin homology-like domain
    cl21485
    Location:111201
    OmpH; Outer membrane protein (OmpH-like)
  3. XM_006520024.2XP_006520087.1  

    Conserved Domains (11) summary
    smart00015
    Location:99121
    IQ; Calmodulin-binding motif
    smart00139
    Location:9111057
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:10661320
    B41; Band 4.1 homologues
    cd13202
    Location:13161404
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:577678
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:743868
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14473
    Location:11681312
    FERM_B-lobe; FERM domain B-lobe
    cl00155
    Location:10631108
    UBQ; Ubiquitin-like proteins
    cl17171
    Location:543585
    PH-like; Pleckstrin homology-like domain
    cl21485
    Location:215305
    OmpH; Outer membrane protein (OmpH-like)
    cl22853
    Location:285
    Motor_domain; Myosin and Kinesin motor domain.
  4. XM_006520026.2XP_006520089.1  

    Conserved Domains (10) summary
    smart00015
    Location:1941
    IQ; Calmodulin-binding motif
    smart00139
    Location:831977
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00295
    Location:9861240
    B41; Band 4.1 homologues
    cd13202
    Location:12361324
    FERM_C_MyoX; FERM domain C-lobe of Myosin X (MyoX, Myo10)
    cd13296
    Location:497598
    PH2_MyoX; Myosin X Pleckstrin homology (PH) domain, repeat 2
    cd13297
    Location:663788
    PH3_MyoX-like; Myosin X-like Pleckstrin homology (PH) domain, repeat 3
    cd14473
    Location:10881232
    FERM_B-lobe; FERM domain B-lobe
    cl00155
    Location:9831028
    UBQ; Ubiquitin-like proteins
    cl17171
    Location:463505
    PH-like; Pleckstrin homology-like domain
    cl21485
    Location:135225
    OmpH; Outer membrane protein (OmpH-like)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    26396055..26587057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)