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Mylpf myosin light chain, phosphorylatable, fast skeletal muscle [ Mus musculus (house mouse) ]

Gene ID: 17907, updated on 8-May-2016
Official Symbol
Mylpfprovided by MGI
Official Full Name
myosin light chain, phosphorylatable, fast skeletal muscleprovided by MGI
Primary source
MGI:MGI:97273
See related
Ensembl:ENSMUSG00000030672 Vega:OTTMUSG00000023131
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mlc2; MLC-2; 2410014J02Rik
Orthologs
Location:
7; 7 F3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (127208848..127214288)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134355122..134357801)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene CD2 antigen (cytoplasmic tail) binding protein 2 Neighboring gene TBC1 domain family, member 10b Neighboring gene septin 1 Neighboring gene predicted gene 4532 Neighboring gene zinc finger protein 553

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Leukocyte transendothelial migration, organism-specific biosystem (from KEGG)
    Leukocyte transendothelial migration, organism-specific biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • Leukocyte transendothelial migration, conserved biosystem (from KEGG)
    Leukocyte transendothelial migration, conserved biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • Muscle contraction, organism-specific biosystem (from REACTOME)
    Muscle contraction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
    Regulation of actin cytoskeleton, organism-specific biosystem
    Regulation of actin cytoskeleton
  • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
    Regulation of actin cytoskeleton, conserved biosystem
    Regulation of actin cytoskeleton
  • Smooth Muscle Contraction, organism-specific biosystem (from REACTOME)
    Smooth Muscle Contraction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Tight junction, organism-specific biosystem (from KEGG)
    Tight junction, organism-specific biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
  • Tight junction, conserved biosystem (from KEGG)
    Tight junction, conserved biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
structural constituent of muscle IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
skeletal muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
myosin complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
myosin regulatory light chain 2, skeletal muscle isoform
Names
MLC2F
fast skeletal myosin light chain 2
myosin light chain 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016754.5NP_058034.1  myosin regulatory light chain 2, skeletal muscle isoform

    See identical proteins and their annotated locations for NP_058034.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122537
    Consensus CDS
    CCDS40140.1
    UniProtKB/Swiss-Prot
    P97457
    UniProtKB/TrEMBL
    Q545G1
    Related
    ENSMUSP00000032910, OTTMUSP00000026815, ENSMUST00000032910, OTTMUST00000055901
    Conserved Domains (2) summary
    PTZ00184
    Location:21157
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:2987
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    127208848..127214288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507421.2XP_006507484.1  

    See identical proteins and their annotated locations for XP_006507484.1

    UniProtKB/TrEMBL
    A0A0U1RP93
    Conserved Domains (2) summary
    PTZ00184
    Location:1137
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:967
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  2. XM_006507422.2XP_006507485.1  

    See identical proteins and their annotated locations for XP_006507485.1

    UniProtKB/TrEMBL
    A0A0U1RP93
    Related
    ENSMUSP00000145886, OTTMUSP00000074893, ENSMUST00000206772, OTTMUST00000143655
    Conserved Domains (2) summary
    PTZ00184
    Location:1137
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:967
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    127060232..127063055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)