Format

Send to:

Choose Destination

Map4 microtubule-associated protein 4 [ Mus musculus (house mouse) ]

Gene ID: 17758, updated on 28-May-2016
Official Symbol
Map4provided by MGI
Official Full Name
microtubule-associated protein 4provided by MGI
Primary source
MGI:MGI:97178
See related
Ensembl:ENSMUSG00000032479 Vega:OTTMUSG00000035845
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MAP-4; Mtap4; Mtap-4; AA407148
Orthologs
Location:
9 F2; 9 59.83 cM
Exon count:
23
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (109931774..110083954)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (109834278..109986451)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene cell division cycle 25A Neighboring gene microRNA 7089 Neighboring gene ribosomal protein L32 pseudogene Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 30 Neighboring gene predicted gene, 39428 Neighboring gene predicted gene 10615

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
tubulin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell division ISO
Inferred from Sequence Orthology
more info
PubMed 
establishment of spindle orientation IDA
Inferred from Direct Assay
more info
PubMed 
establishment of spindle orientation ISO
Inferred from Sequence Orthology
more info
PubMed 
microtubule sliding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule sliding ISO
Inferred from Sequence Orthology
more info
PubMed 
mitotic spindle organization IDA
Inferred from Direct Assay
more info
PubMed 
mitotic spindle organization ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of nonmotile primary cilium assembly ISO
Inferred from Sequence Orthology
more info
 
neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
axoneme ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
microtubule associated complex IBA
Inferred from Biological aspect of Ancestor
more info
 
microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
mitotic spindle ISO
Inferred from Sequence Orthology
more info
PubMed 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
 
neuronal postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
microtubule-associated protein 4
Names
MAP 4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205330.1NP_001192259.1  microtubule-associated protein 4 isoform 1

    See identical proteins and their annotated locations for NP_001192259.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes isoform (1).
    Source sequence(s)
    AC161246
    Consensus CDS
    CCDS57704.1
    UniProtKB/Swiss-Prot
    P27546
    Related
    ENSMUSP00000035055, OTTMUSP00000050617, ENSMUST00000035055, OTTMUST00000091828
    Conserved Domains (1) summary
    pfam00418
    Location:965995
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  2. NM_001205331.1NP_001192260.1  microtubule-associated protein 4 isoform 3

    See identical proteins and their annotated locations for NP_001192260.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC161246, AK046825
    Consensus CDS
    CCDS57703.1
    UniProtKB/TrEMBL
    Q78TF3
    Related
    ENSMUSP00000131660, OTTMUSP00000069800, ENSMUST00000169851, OTTMUST00000130117
  3. NM_001205332.1NP_001192261.1  microtubule-associated protein 4 isoform 4

    See identical proteins and their annotated locations for NP_001192261.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 3' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 4) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC161246, BC050893
    UniProtKB/Swiss-Prot
    P27546
    Conserved Domains (1) summary
    pfam00418
    Location:927957
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  4. NM_001311163.1NP_001298092.1  microtubule-associated protein 4 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' and 3' UTRs and has multiple coding region differences, including use of an alternate translation initiation site compared to variant 1. It encodes isoform 5, which is shorter than and has distinct N- and C-termini compared to isoform 1.
    Source sequence(s)
    AK146790, BB526067, BC042645, BY125595
    Consensus CDS
    CCDS81082.1
    UniProtKB/Swiss-Prot
    P27546
    UniProtKB/TrEMBL
    E9PZ43
    Conserved Domains (1) summary
    pfam00418
    Location:774804
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  5. NM_001311164.1NP_001298093.1  microtubule-associated protein 4 isoform 6

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' and 3' UTRs and has multiple coding region differences, including use of an alternate translation initiation site compared to variant 1. It encodes isoform 6, which is shorter than and has distinct N- and C-termini compared to isoform 1.
    Source sequence(s)
    AK166558, BB526067, BC042645, BY125595
    Consensus CDS
    CCDS81083.1
    UniProtKB/Swiss-Prot
    P27546
    UniProtKB/TrEMBL
    A0A0G2JDN7
    Conserved Domains (1) summary
    pfam00418
    Location:774804
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  6. NM_008633.4NP_032659.2  microtubule-associated protein 4 isoform 2

    See identical proteins and their annotated locations for NP_032659.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is the same length as isoform 1.
    Source sequence(s)
    AC161246, BC044654
    UniProtKB/Swiss-Prot
    P27546
    Related
    ENSMUSP00000132662, OTTMUSP00000050618, ENSMUST00000165876, OTTMUST00000091829
    Conserved Domains (1) summary
    pfam00418
    Location:965995
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    109931774..110083954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511955.1XP_006512018.1  

    See identical proteins and their annotated locations for XP_006512018.1

    Conserved Domains (1) summary
    pfam00418
    Location:965995
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  2. XM_006511967.1XP_006512030.1  

    See identical proteins and their annotated locations for XP_006512030.1

    UniProtKB/TrEMBL
    Q78TF3
  3. XM_006511956.1XP_006512019.1  

    See identical proteins and their annotated locations for XP_006512019.1

    Conserved Domains (1) summary
    pfam00418
    Location:965995
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  4. XM_011242936.1XP_011241238.1  

    Conserved Domains (1) summary
    pfam00418
    Location:927957
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  5. XM_011242937.1XP_011241239.1  

    Conserved Domains (1) summary
    pfam00418
    Location:927957
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  6. XM_011242938.1XP_011241240.1  

  7. XM_006511964.2XP_006512027.1  

    Conserved Domains (1) summary
    pfam00418
    Location:738768
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  8. XM_006511960.2XP_006512023.1  

    Conserved Domains (1) summary
    pfam00418
    Location:812842
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  9. XM_006511961.2XP_006512024.1  

    Related
    ENSMUSP00000131285, OTTMUSP00000050620, ENSMUST00000164930, OTTMUST00000091831
    Conserved Domains (1) summary
    pfam00418
    Location:774804
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  10. XM_006511963.2XP_006512026.1  

    Related
    ENSMUSP00000142439, OTTMUSP00000050621, ENSMUST00000199498, OTTMUST00000091832
    Conserved Domains (1) summary
    pfam00418
    Location:774804
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
  11. XM_006511962.2XP_006512025.1  

    Conserved Domains (1) summary
    pfam00418
    Location:774804
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    109659367..109812153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)