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Map2 microtubule-associated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 17756, updated on 21-Apr-2024

Summary

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Official Symbol
Map2provided by MGI
Official Full Name
microtubule-associated protein 2provided by MGI
Primary source
MGI:MGI:97175
See related
Ensembl:ENSMUSG00000015222 AllianceGenome:MGI:97175
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
Summary
Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; negative regulation of axon extension; and regulation of protein localization. Acts upstream of or within several processes, including establishment of cell polarity; microtubule bundle formation; and neuron projection development. Located in several cellular components, including axon; dendrite; and proximal neuron projection. Is expressed in several structures, including back skin; central nervous system; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human MAP2 (microtubule associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 41.7), frontal lobe adult (RPKM 39.0) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 C3; 1 33.49 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (66214337..66481742)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (66175202..66442583)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene cell growth-regulating nucleolar protein Neighboring gene STARR-seq mESC enhancer starr_01184 Neighboring gene predicted gene 8812 Neighboring gene STARR-seq mESC enhancer starr_01185 Neighboring gene predicted gene, 51629 Neighboring gene predicted gene, 24729 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_01187 Neighboring gene STARR-seq mESC enhancer starr_01188 Neighboring gene predicted gene, 25411 Neighboring gene STARR-seq mESC enhancer starr_01189 Neighboring gene unc-80, NALCN activator Neighboring gene STARR-seq mESC enhancer starr_01190 Neighboring gene predicted gene, 39655 Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene ribulose-5-phosphate-3-epimerase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. MAP2 is differentially phosphorylated in schizophrenia, altering its function. Grubisha MJ, et al. Mol Psychiatry, 2021 Sep. PMID 33526823, Free PMC Article
  2. A Mutation in Mtap2 Is Associated with Arrest of Mammalian Spermatocytes before the First Meiotic Division. Sun F, et al. Genes (Basel), 2011 Mar 1. PMID 24501684, Free PMC Article
  3. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. Takahashi RH, et al. PLoS One, 2013. PMID 23372648, Free PMC Article
  4. Reduced expression of kinase-associated phosphatase in cortical dendrites of MAP2-deficient mice. Iriuchijima N, et al. Biochem Biophys Res Commun, 2005 Dec 16. PMID 16257389
  5. Transient loss of microtubule-associated protein 2 immunoreactivity after moderate brain injury in mice. Huh JW, et al. J Neurotrauma, 2003 Oct. PMID 14588114

See all (527) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MAP2 is differentially phosphorylated in schizophrenia, altering its function.
    Title: MAP2 is differentially phosphorylated in schizophrenia, altering its function.
  2. Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
    Title: Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
  3. MAP2c levels in different brain regions of aging mice were positively correlated with neuropsin expression.
    Title: Neuropsin Expression Correlates with Dendritic Marker MAP2c Level in Different Brain Regions of Aging Mice.
  4. Accumulation of intraneuronal beta-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
    Title: Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
  5. results demonstrate the structural and functional determinant underlying the v-KIND-MAP2 interaction that controls dendrite arborization patterns
    Title: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.
  6. Increased MAP2 expression in malignant melanoma cells significantly inhibits tumor cell growth and neoplasm invasiveness, and induces apoptosis and cell cycle arrest.
    Title: Increased expression of MAP2 inhibits melanoma cell proliferation, invasion and tumor growth in vitro and in vivo.
  7. Data show that inhibition of ZNF238 (RP58) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN and downregulates the expression of the cell cycle arrest protein p27, a regulator of GNP differentiation.
    Title: ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.
  8. AKAP150 and Mtap2 put TREK channels at the center of a complex protein network that finely tunes channel trafficking, addressing, and regulation.
    Title: Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.
  9. v-KIND mediates a signaling pathway that links Ras and MAP2 to control dendrite growth
    Title: Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2.
  10. JNK1 phosphorylation of MAP2 plays an important role in defining dendritic architecture in the brain.
    Title: Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector.
Submit: New GeneRIF Correction See all GeneRIFs (18)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (4) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding ISO
Inferred from Sequence Orthology
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal regulatory protein binding TAS
Traceable Author Statement
more info
 PubMed 
enables dystroglycan binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within axonogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within axonogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to organic substance IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within dendrite development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microtubule bundle formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of axon extension ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of microtubule depolymerization ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of microtubule polymerization ISO
Inferred from Sequence Orthology
more info
  
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of anterograde dense core granule transport ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of anterograde synaptic vesicle transport ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of organelle transport along microtubule ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of protein localization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in CA3 pyramidal cell dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in apical dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in apical distal dendrite ISO
Inferred from Sequence Orthology
more info
  
located_in axon hillock IDA
Inferred from Direct Assay
more info
 PubMed 
located_in axon hillock ISO
Inferred from Sequence Orthology
more info
  
located_in axon initial segment IDA
Inferred from Direct Assay
more info
 PubMed 
located_in axon initial segment ISO
Inferred from Sequence Orthology
more info
  
located_in basal dendrite ISO
Inferred from Sequence Orthology
more info
  
is_active_in cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in dendrite cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in dendritic branch ISO
Inferred from Sequence Orthology
more info
  
located_in dendritic filopodium ISO
Inferred from Sequence Orthology
more info
  
located_in dendritic growth cone ISO
Inferred from Sequence Orthology
more info
  
located_in dendritic shaft IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendritic shaft ISO
Inferred from Sequence Orthology
more info
  
located_in distal dendrite ISO
Inferred from Sequence Orthology
more info
  
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular anatomical structure IDA
Inferred from Direct Assay
more info
 PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
part_of microtubule associated complex TAS
Traceable Author Statement
more info
 PubMed 
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuron projection IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in postsynapse ISO
Inferred from Sequence Orthology
more info
  
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
located_in primary dendrite ISO
Inferred from Sequence Orthology
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  
located_in proximal dendrite ISO
Inferred from Sequence Orthology
more info
  
located_in proximal neuron projection IDA
Inferred from Direct Assay
more info
 PubMed 
located_in proximal neuron projection ISO
Inferred from Sequence Orthology
more info
  
located_in ruffle membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
microtubule-associated protein 2

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039934.1 → NP_001035023.1  microtubule-associated protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001035023.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, lacks a large in-frame segment, and contains an alternate in-frame exon compared to variant 3. The resulting isoform (1) has the same N- and C-termini but is much shorter compared to isoform 3.
    Source sequence(s)
    AC091465, AW124823, BU056737, CD348897, CN533265, CN538992
    Consensus CDS
    CCDS15020.1
    UniProtKB/TrEMBL
    B2KGT5, Q3TLQ0, Q80X35
    Related
    ENSMUSP00000109650.2, ENSMUST00000114017.8
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  2. NM_001310634.1 → NP_001297563.1  microtubule-associated protein 2 isoform 3

    See identical proteins and their annotated locations for NP_001297563.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
    Source sequence(s)
    AK141458, BC052446, CF538767, CV558214
    Consensus CDS
    CCDS83550.1
    UniProtKB/Swiss-Prot
    E9QLE1, P20357
    UniProtKB/TrEMBL
    A0A668KLC6
    Related
    ENSMUSP00000109646.2, ENSMUST00000114013.8
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  3. NM_008632.2 → NP_032658.2  microtubule-associated protein 2 isoform 2

    See identical proteins and their annotated locations for NP_032658.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and lacks a large in-frame segment compared to variant 3. The resulting isoform (2) has the same N- and C-termini but is much shorter compared to isoform 3.
    Source sequence(s)
    BC052446
    Consensus CDS
    CCDS35602.1
    UniProtKB/TrEMBL
    B2KGT5, Q80X35, Q80ZL4
    Related
    ENSMUSP00000109648.2, ENSMUST00000114015.8
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    66214337..66481742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006495762.5 → XP_006495825.1  microtubule-associated protein 2 isoform X17

    See identical proteins and their annotated locations for XP_006495825.1

    UniProtKB/TrEMBL
    B2KGT5, Q80X35, Q80ZL4
    Related
    ENSMUSP00000024639.6, ENSMUST00000024639.12
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  2. XM_036162607.1 → XP_036018500.1  microtubule-associated protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A668KLC6
    Related
    ENSMUSP00000159224.2, ENSMUST00000239213.2
    Conserved Domains (2) summary
    pfam08377
    Location:458 → 1592
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1806 → 1837
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  3. XM_006495746.4 → XP_006495809.1  microtubule-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006495809.1

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  4. XM_006495754.4 → XP_006495817.1  microtubule-associated protein 2 isoform X7

    See identical proteins and their annotated locations for XP_006495817.1

    UniProtKB/Swiss-Prot
    E9QLE1, P20357
    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  5. XM_006495751.4 → XP_006495814.1  microtubule-associated protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  6. XM_006495756.4 → XP_006495819.1  microtubule-associated protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  7. XM_006495750.4 → XP_006495813.1  microtubule-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1509
    MAP2_projctn; MAP2/Tau projection domain

  8. XM_017319166.3 → XP_017174655.1  microtubule-associated protein 2 isoform X8

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1509
    MAP2_projctn; MAP2/Tau projection domain

  9. XM_006495752.4 → XP_006495815.1  microtubule-associated protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1691 → 1720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1509
    MAP2_projctn; MAP2/Tau projection domain

  10. XM_017319175.3 → XP_017174664.1  microtubule-associated protein 2 isoform X10

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1691 → 1720
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1509
    MAP2_projctn; MAP2/Tau projection domain

  11. XM_006495753.4 → XP_006495816.1  microtubule-associated protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1506
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1689 → 1719
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  12. XM_006495757.4 → XP_006495820.1  microtubule-associated protein 2 isoform X11

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1689 → 1718
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:372 → 1506
    MAP2_projctn; MAP2/Tau projection domain

  13. XM_036162582.1 → XP_036018475.1  microtubule-associated protein 2 isoform X13

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1506
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1719 → 1750
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  14. XM_036162575.1 → XP_036018468.1  microtubule-associated protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1505
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1688 → 1718
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  15. XM_036162581.1 → XP_036018474.1  microtubule-associated protein 2 isoform X12

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1505
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1719 → 1750
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  16. XM_006495759.5 → XP_006495822.1  microtubule-associated protein 2 isoform X15

    See identical proteins and their annotated locations for XP_006495822.1

    UniProtKB/TrEMBL
    B2KGT5, Q3TLQ0, Q80X35
    Related
    ENSMUSP00000109651.4, ENSMUST00000114018.10
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  17. XM_006495761.5 → XP_006495824.1  microtubule-associated protein 2 isoform X16

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:331 → 360
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  18. XM_036162601.1 → XP_036018494.1  microtubule-associated protein 2 isoform X18

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:362 → 393
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  19. XM_011238448.3 → XP_011236750.1  microtubule-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011236750.1

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  20. XM_030251990.2 → XP_030107850.1  microtubule-associated protein 2 isoform X16

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:331 → 360
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  21. XM_030251982.1 → XP_030107842.1  microtubule-associated protein 2 isoform X15

    UniProtKB/TrEMBL
    B2KGT5, Q3TLQ0, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  22. XM_006495748.5 → XP_006495811.1  microtubule-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006495811.1

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  23. XM_006495749.5 → XP_006495812.1  microtubule-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006495812.1

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  24. XM_036162573.1 → XP_036018466.1  microtubule-associated protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1506
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1689 → 1719
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  25. XM_030251986.2 → XP_030107846.1  microtubule-associated protein 2 isoform X15

    UniProtKB/TrEMBL
    B2KGT5, Q3TLQ0, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  26. XM_030251996.2 → XP_030107856.1  microtubule-associated protein 2 isoform X17

    UniProtKB/TrEMBL
    B2KGT5, Q80X35, Q80ZL4
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  27. XM_030251993.2 → XP_030107853.1  microtubule-associated protein 2 isoform X16

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:331 → 360
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  28. XM_006495747.5 → XP_006495810.1  microtubule-associated protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006495810.1

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1693 → 1722
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  29. XM_017319165.3 → XP_017174654.1  microtubule-associated protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  30. XM_017319169.3 → XP_017174658.1  microtubule-associated protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1692 → 1721
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:376 → 1510
    MAP2_projctn; MAP2/Tau projection domain

  31. XM_030251971.2 → XP_030107831.1  microtubule-associated protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam08377
    Location:372 → 1506
    MAP2_projctn; MAP2/Tau projection domain
    pfam00418
    Location:1689 → 1719
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  32. XM_006495760.3 → XP_006495823.1  microtubule-associated protein 2 isoform X15

    See identical proteins and their annotated locations for XP_006495823.1

    UniProtKB/TrEMBL
    B2KGT5, Q3TLQ0, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  33. XM_017319194.3 → XP_017174683.1  microtubule-associated protein 2 isoform X17

    UniProtKB/TrEMBL
    B2KGT5, Q80X35, Q80ZL4
    Conserved Domains (1) summary
    pfam00418
    Location:332 → 361
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  34. XM_030251989.2 → XP_030107849.1  microtubule-associated protein 2 isoform X16

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:331 → 360
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  35. XM_036162604.1 → XP_036018497.1  microtubule-associated protein 2 isoform X18

    UniProtKB/TrEMBL
    B2KGT5, Q80X35
    Conserved Domains (1) summary
    pfam00418
    Location:362 → 393
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

  36. XM_006495758.5 → XP_006495821.1  microtubule-associated protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1535 → 1564
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:218 → 1352
    MAP2_projctn; MAP2/Tau projection domain

  37. XM_030251978.2 → XP_030107838.1  microtubule-associated protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1535 → 1564
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:218 → 1352
    MAP2_projctn; MAP2/Tau projection domain

  38. XM_030251976.2 → XP_030107836.1  microtubule-associated protein 2 isoform X14

    UniProtKB/TrEMBL
    A0A668KLC6
    Conserved Domains (2) summary
    pfam00418
    Location:1535 → 1564
    Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    pfam08377
    Location:218 → 1352
    MAP2_projctn; MAP2/Tau projection domain

RNA

  1. XR_004940738.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P20357.2 GenPept UniProtKB/Swiss-Prot:P20357

Gene LinkOut

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