rps-0 Ribosomal Protein, Small subunit [Caenorhabditis elegans] - Gene

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Summary

Gene symbol: rps-0
Gene description: Ribosomal Protein, Small subunit
Primary source: WormBase:WBGene00004469
Locus tag: B0393.1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

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Genomic context

Sequence :: Chromosome: III; NC_003281.8 (4752962..4754047, complement)

See rps-0 in MapViewer

Chromosome III - NC_003281.8 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:40862	BioGRID:38676	ZK849.1	BioGRID	PubMed	Two-hybrid
BioGRID:40862	BioGRID:40947	atp-2	BioGRID	PubMed	Two-hybrid
BioGRID:40862	BioGRID:45907	bar-1	BioGRID	PubMed	Negative Genetic
BioGRID:40862	BioGRID:40655	daf-2	BioGRID	PubMed	Negative Genetic
BioGRID:40862	BioGRID:54272	ndx-4	BioGRID	PubMed	Two-hybrid
BioGRID:40862	BioGRID:41690	ran-1	BioGRID	PubMed	Two-hybrid
BioGRID:40862	BioGRID:41223	rps-21	BioGRID	PubMed	Two-hybrid
BioGRID:40862	BioGRID:45777	tag-257	BioGRID	PubMed	Two-hybrid

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General gene information

Markers

B0393.1 (e-PCR)
- UniSTS:306037

Homology

Homologs of the rps-0 gene: The rps-0 gene is conserved in human, chimpanzee, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, rice, and P.falciparum.

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem (from WikiPathways)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem
Cytoplasmic Ribosomal Proteins
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Termination, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Termination, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of a pool of free 40S subunits, organism-specific biosystem (from REACTOME)
Formation of a pool of free 40S subunits, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem (from REACTOME)
Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosomal scanning and start codon recognition, organism-specific biosystem (from REACTOME)
Ribosomal scanning and start codon recognition, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
protein binding	IPI Inferred from Physical Interaction more info	PubMed
structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
structural constituent of ribosome	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
apoptotic process	IMP Inferred from Mutant Phenotype more info
embryo development ending in birth or egg hatching	IMP Inferred from Mutant Phenotype more info	PubMed
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
growth	IMP Inferred from Mutant Phenotype more info	PubMed
hermaphrodite genitalia development	IMP Inferred from Mutant Phenotype more info	PubMed
molting cycle, collagen and cuticulin-based cuticle	IMP Inferred from Mutant Phenotype more info	PubMed
nematode larval development	IMP Inferred from Mutant Phenotype more info	PubMed
rRNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
reproduction	IMP Inferred from Mutant Phenotype more info	PubMed
ribosomal small subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
translation	IBA Inferred from Biological aspect of Ancestor more info
translation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
90S preribosome	IBA Inferred from Biological aspect of Ancestor more info
cytosolic small ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
intracellular	IEA Inferred from Electronic Annotation more info	PubMed
ribosome	IEA Inferred from Electronic Annotation more info	PubMed
small ribosomal subunit	IEA Inferred from Electronic Annotation more info	PubMed

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General protein information

Names: Ribosomal Protein, Small subunit family member (rps-0)

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.8

Range

4752962..4754047, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065577.4 → NP_497978.1 Ribosomal Protein, Small subunit family member (rps-0) [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

P46769

Conserved Domains (1) summary

cd01425
Location:18 – 183
Blast Score: 520

RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...