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M106.3 Prostaglandin reductase 2 [ Caenorhabditis elegans ]

Gene ID: 174671, updated on 23-Nov-2023

Summary

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Gene symbol
M106.3
Gene description
Prostaglandin reductase 2
Primary source
WormBase:WBGene00010911
Locus tag
CELE_M106.3
See related
AllianceGenome:WB:WBGene00010911
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable 15-oxoprostaglandin 13-oxidase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and vulval muscle. Orthologous to several human genes including PTGR2 (prostaglandin reductase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See M106.3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (10857442..10860909, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Regulatory protein zeste Neighboring gene DNA-directed RNA polymerase III subunit RPC9 Neighboring gene putative GMP synthase [glutamine-hydrolyzing] Neighboring gene ncRNA Neighboring gene F-actin-capping protein subunit beta Neighboring gene Peptidyl-prolyl cis-trans isomerase 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 13-prostaglandin reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables 15-oxoprostaglandin 13-oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 15-oxoprostaglandin 13-oxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in prostaglandin metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in prostaglandin metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Prostaglandin reductase 2
NP_001076630.1
  • Confirmed by transcript evidence
NP_001379459.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10857442..10860909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393183.1 → NP_001379459.1  Prostaglandin reductase 2 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0G840
    Conserved Domains (1) summary
    cd08293
    Location:22 → 373
    PTGR2; Prostaglandin reductase

  2. NM_001083161.4 → NP_001076630.1  Prostaglandin reductase 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001076630.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0G839
    Conserved Domains (1) summary
    cd08293
    Location:14 → 365
    PTGR2; Prostaglandin reductase
Nucleotide Protein
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