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ceh-38 Homeobox protein ceh-38;One cut domain family member [ Caenorhabditis elegans ]

Gene ID: 174136, updated on 23-Nov-2023

Summary

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Gene symbol
ceh-38
Gene description
Homeobox protein ceh-38;One cut domain family member
Primary source
WormBase:WBGene00000459
Locus tag
CELE_F22D3.1
See related
AllianceGenome:WB:WBGene00000459
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including body wall musculature; digestive tract; hypodermis; neurons; and somatic nervous system. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (6951526..6955409)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Folliculin;Folliculin DENN domain-containing protein;UDENN FLCN/SMCR8-type domain-containing protein Neighboring gene miscRNA Neighboring gene Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Neighboring gene Sex-determining transformer protein 2 Neighboring gene putative translation initiation factor eIF-2B subunit gamma Neighboring gene ncRNA Neighboring gene RING-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rapid expression screening of Caenorhabditis elegans homeobox open reading frames using a two-step polymerase chain reaction promoter-gfp reporter construction technique. Cassata G, et al. Gene, 1998 May 28. PMID 9661672
  2. Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins. Lannoy VJ, et al. J Biol Chem, 1998 May 29. PMID 9593691
  3. Loss and gain of domains during evolution of cut superclass homeobox genes. Bürglin TR, et al. Int J Dev Biol, 2002 Jan. PMID 11902672
  4. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Couillault C, et al. Nat Immunol, 2004 May. PMID 15048112
  5. The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells. Lin B, et al. Dev Biol, 2008 Apr 1. PMID 18304523, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Homeobox protein ceh-38;One cut domain family member
NP_001338814.1
  • Confirmed by transcript evidence
NP_001338820.1
  • Confirmed by transcript evidence
NP_001338821.1
  • Confirmed by transcript evidence
NP_001367332.1
  • Confirmed by transcript evidence
NP_001368648.1
  • Confirmed by transcript evidence
NP_001368649.1
  • Confirmed by transcript evidence
NP_001368650.1
  • Confirmed by transcript evidence
NP_001368651.1
  • Confirmed by transcript evidence
NP_001368652.1
  • Confirmed by transcript evidence
NP_001368653.1
  • Confirmed by transcript evidence
NP_001368654.1
  • Confirmed by transcript evidence
NP_001368655.1
  • Confirmed by transcript evidence
NP_001368656.1
  • Confirmed by transcript evidence
NP_001368657.1
  • Confirmed by transcript evidence
NP_001370972.1
  • Confirmed by transcript evidence
NP_741018.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6951526..6955409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001351914.2 → NP_001338821.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBM0
    Conserved Domains (2) summary
    smart00389
    Location:429 → 485
    HOX; Homeodomain
    pfam02376
    Location:313 → 389
    CUT; CUT domain

  2. NM_001381475.2 → NP_001368651.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RC50
    Conserved Domains (2) summary
    smart00389
    Location:421 → 477
    HOX; Homeodomain
    pfam02376
    Location:307 → 384
    CUT; CUT domain

  3. NM_001381472.2 → NP_001368657.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBK4
    Conserved Domains (2) summary
    smart00389
    Location:430 → 486
    HOX; Homeodomain
    pfam02376
    Location:316 → 393
    CUT; CUT domain

  4. NM_171852.2 → NP_741018.1  Homeobox protein ceh-38 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741018.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19720
    Conserved Domains (2) summary
    smart00389
    Location:418 → 474
    HOX; Homeodomain
    pfam02376
    Location:304 → 380
    CUT; CUT domain

  5. NM_001381471.2 → NP_001368648.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBJ2
    Conserved Domains (2) summary
    smart00389
    Location:430 → 486
    HOX; Homeodomain
    pfam02376
    Location:316 → 393
    CUT; CUT domain

  6. NM_001381477.2 → NP_001367332.1  Homeobox protein ceh-38 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19720, Q95QJ5
    Conserved Domains (2) summary
    smart00389
    Location:427 → 483
    HOX; Homeodomain
    pfam02376
    Location:313 → 390
    CUT; CUT domain

  7. NM_001381476.1 → NP_001368652.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBR4
    Conserved Domains (2) summary
    smart00389
    Location:421 → 477
    HOX; Homeodomain
    pfam02376
    Location:307 → 384
    CUT; CUT domain

  8. NM_001351913.3 → NP_001338820.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBK3
    Conserved Domains (2) summary
    smart00389
    Location:429 → 485
    HOX; Homeodomain
    pfam02376
    Location:313 → 389
    CUT; CUT domain

  9. NM_001381478.2 → NP_001368653.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBS0
    Conserved Domains (2) summary
    smart00389
    Location:427 → 483
    HOX; Homeodomain
    pfam02376
    Location:313 → 390
    CUT; CUT domain

  10. NM_001381480.1 → NP_001368655.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RCV1
    Conserved Domains (2) summary
    smart00389
    Location:420 → 476
    HOX; Homeodomain
    pfam02376
    Location:304 → 381
    CUT; CUT domain

  11. NM_001381479.1 → NP_001368654.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBN7
    Conserved Domains (2) summary
    smart00389
    Location:420 → 476
    HOX; Homeodomain
    pfam02376
    Location:304 → 381
    CUT; CUT domain

  12. NM_001381473.2 → NP_001368649.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBJ5
    Conserved Domains (2) summary
    smart00389
    Location:423 → 479
    HOX; Homeodomain
    pfam02376
    Location:307 → 384
    CUT; CUT domain

  13. NM_001351905.5 → NP_001338814.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RCT5
    Conserved Domains (2) summary
    smart00389
    Location:432 → 488
    HOX; Homeodomain
    pfam02376
    Location:316 → 392
    CUT; CUT domain

  14. NM_001383875.2 → NP_001370972.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBM7
    Conserved Domains (2) summary
    smart00389
    Location:432 → 488
    HOX; Homeodomain
    pfam02376
    Location:316 → 393
    CUT; CUT domain

  15. NM_001381481.1 → NP_001368656.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RBK2
    Conserved Domains (2) summary
    smart00389
    Location:418 → 474
    HOX; Homeodomain
    pfam02376
    Location:304 → 381
    CUT; CUT domain

  16. NM_001381474.1 → NP_001368650.1  One cut domain family member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X7RC48
    Conserved Domains (2) summary
    smart00389
    Location:423 → 479
    HOX; Homeodomain
    pfam02376
    Location:307 → 384
    CUT; CUT domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q19720.2
T16136.1

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