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Kitl kit ligand [ Mus musculus (house mouse) ]

Gene ID: 17311, updated on 27-Jun-2015
Official Symbol
Kitlprovided by MGI
Official Full Name
kit ligandprovided by MGI
Primary source
MGI:MGI:96974
See related
Ensembl:ENSMUSG00000019966; Vega:OTTMUSG00000020799
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted
Orthologs
See Kitl in Epigenomics, MapViewer
Location:
10 D1; 10 51.4 cM
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (100015809..100100416)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (99478458..99563046)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35437 Neighboring gene keratin 18 pseudogene Neighboring gene predicted gene, 35533 Neighboring gene THO complex 4 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
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Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cytokine activity IDA
Inferred from Direct Assay
more info
PubMed 
growth factor activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
stem cell factor receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
ectopic germ cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway in absence of ligand IDA
Inferred from Direct Assay
more info
PubMed 
germ cell development TAS
Traceable Author Statement
more info
PubMed 
negative regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of mast cell apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
neural crest cell migration IDA
Inferred from Direct Assay
more info
PubMed 
ovarian follicle development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA replication ISO
Inferred from Sequence Orthology
more info
 
positive regulation of MAP kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of Ras protein signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of leukocyte migration IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of mast cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of melanocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of myeloid leukocyte differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
kit ligand
Names
kit ligand
C-kit ligand
Steel factor
cloud gray
grizzle-belly
hematopoietic growth factor KL
mast cell growth factor
stem cell factor
NP_038626.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013598.2NP_038626.1  kit ligand precursor

    See identical proteins and their annotated locations for NP_038626.1

    Status: VALIDATED

    Source sequence(s)
    AC159910, U44725
    Consensus CDS
    CCDS36046.1
    UniProtKB/Swiss-Prot
    P20826
    Related
    ENSMUSP00000100920, OTTMUSP00000022753, ENSMUST00000105283, OTTMUST00000049195
    Conserved Domains (1) summary
    pfam02404
    Location:1273
    SCF; Stem cell factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    100015809..100100416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513314.2XP_006513377.1  

    Conserved Domains (1) summary
    pfam02404
    Location:46313
    SCF; Stem cell factor
  2. XM_006513315.2XP_006513378.1  

    Conserved Domains (1) summary
    pfam02404
    Location:46285
    SCF; Stem cell factor

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    101983926..102068221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)