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rla-0 Large ribosomal subunit protein uL10 [ Caenorhabditis elegans ]

Gene ID: 172943, updated on 23-Nov-2023

Summary

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Gene symbol
rla-0
Gene description
Large ribosomal subunit protein uL10
Primary source
WormBase:WBGene00004408
Locus tag
CELE_F25H2.10
See related
AllianceGenome:WB:WBGene00004408
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in several structures, including anal depressor muscle; intestine; nervous system; pharynx; and tail. Orthologous to several human genes including RPLP0 (ribosomal protein lateral stalk subunit P0). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (10567894..10569017)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Proteasome subunit alpha type-5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Translationally-controlled tumor protein homolog Neighboring gene Methyltransferase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cholesterol-responsive metabolic proteins are required for larval development in Caenorhabditis elegans. Kawasaki I, et al. Mol Cells, 2013 Nov. PMID 24218109, Free PMC Article
  2. CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity. Pal S, et al. Curr Biol, 2017 Mar 20. PMID 28285997
  3. Analysis of acidic peptides with a matrix-assisted laser desorption/ionization mass spectrometry using positive and negative ion modes with additive monoammonium phosphate. Nabetani T, et al. Proteomics, 2006 Aug. PMID 16897684
  4. SKIP and BIR-1/Survivin have potential to integrate proteome status with gene expression. Kostrouch D, et al. J Proteomics, 2014 Oct 14. PMID 25088050
  5. Caenorhabditis elegans operons: form and function. Blumenthal T, et al. Nat Rev Genet, 2003 Feb. PMID 12560808

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables large ribosomal subunit rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Large ribosomal subunit protein uL10
NP_492766.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10567894..10569017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060365.11 → NP_492766.1  Large ribosomal subunit protein uL10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492766.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93572
    Conserved Domains (3) summary
    cd05795
    Location:9 → 182
    Ribosomal_P0_L10e; Ribosomal protein L10 family, P0 and L10e subfamily; composed of eukaryotic 60S ribosomal protein P0 and the archaeal P0 homolog, L10e. P0 or L10e forms a tight complex with multiple copies of the small acidic protein L12(e). This complex forms a stalk ...
    PTZ00135
    Location:1 → 312
    PTZ00135; 60S acidic ribosomal protein P0; Provisional
    pfam00428
    Location:232 → 311
    Ribosomal_60s; 60s Acidic ribosomal protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93572.3

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