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Mcm4 minichromosome maintenance complex component 4 [ Mus musculus (house mouse) ]

Gene ID: 17217, updated on 8-May-2016
Official Symbol
Mcm4provided by MGI
Official Full Name
minichromosome maintenance complex component 4provided by MGI
Primary source
MGI:MGI:103199
See related
Ensembl:ENSMUSG00000022673
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
19G; Cdc21; Mcmd4; mcdc21; AI325074; AU045576; mKIAA4003
Orthologs
Location:
16 10.09 cM; 16 B1
Exon count:
16
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (15623897..15637400, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (15623990..15637493, complement)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 Neighboring gene predicted gene 7748 Neighboring gene protein kinase, DNA activated, catalytic polypeptide Neighboring gene mitotic spindle organizing protein 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA4003

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to ATP-dependent DNA helicase activity ISO
Inferred from Sequence Orthology
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
single-stranded DNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA replication IEA
Inferred from Electronic Annotation
more info
 
DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 
DNA unwinding involved in DNA replication IPI
Inferred from Physical Interaction
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
MCM complex ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
DNA replication licensing factor MCM4
Names
CDC21 homolog
P1-CDC21
mini chromosome maintenance deficient 4 homolog
minichromosome maintenance deficient 4 homolog
NP_032591.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008565.3NP_032591.3  DNA replication licensing factor MCM4

    See identical proteins and their annotated locations for NP_032591.3

    Status: VALIDATED

    Source sequence(s)
    AK036653, AK141644, AK151499
    Consensus CDS
    CCDS27977.1
    UniProtKB/Swiss-Prot
    P49717
    UniProtKB/TrEMBL
    Q3UA65, Q542F4
    Related
    ENSMUSP00000023353, ENSMUST00000023353
    Conserved Domains (3) summary
    cd00009
    Location:504649
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00350
    Location:266769
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:161286
    MCM_N; MCM N-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    15623897..15637400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    16200304..16213825 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)