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    icp-1 InCenP homolog [ Caenorhabditis elegans ]

    Gene ID: 171788, updated on 6-May-2012
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    Summary

    Gene symbol
    icp-1
    Gene description
    InCenP homolog
    Primary source
    WormBase:WBGene00002047
    Locus tag
    Y39G10AR.13
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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    Genomic context

    Location :
    chromosome: I
    Sequence :
    Chromosome: I; NC_003279.6 (2304513..2306817, complement)
    See icp-1 in MapViewer

    Chromosome I - NC_003279.6Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene TPX2 (Targeting Protein for Xenopus Klp2)-Like Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475.
    2. Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Balklava Z, et al. Nat Cell Biol, 2007 Sep. PMID 17704769.
    3. The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase. Han Z, et al. Curr Biol, 2005 May 24. PMID 15916946.
    4. lis-1 is required for dynein-dependent cell division processes in C. elegans embryos. Cockell MM, et al. J Cell Sci, 2004 Sep 1. PMID 15331665.
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431.

    See all (9) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_490956.1 NP_491714.1 air-2    BIND  PubMed AIR-2 phosphorylates and forms a kinase complex with ICP-1. 
    BioGRID:37274 BioGRID:50067 F35E2.9    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:42867 T20D3.3    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:42805 T28C6.7    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:44244 air-1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:37274 BioGRID:37722 air-2    BioGRID  PubMed Reconstituted Complex; Two-hybrid 
    BioGRID:37274 BioGRID:44622 bir-1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:37274 BioGRID:40295 csc-1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:37274 BioGRID:39676 cut-3    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:44995 fib-1    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:45676 flp-11    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:39880 lec-2    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:40702 nhr-6    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:42959 pyp-1    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:39572 rpa-1    BioGRID  PubMed Two-hybrid 
    BioGRID:37274 BioGRID:42052 rpl-15    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    receptor-mediated endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    reproduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Names
    InCenP homolog family member (icp-1)
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.6

      Range
      2304513..2306817, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058555.7 → NP_490956.1  InCenP homolog family member (icp-1) [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EE37
      Conserved Domains (1) summary
      pfam03941
      Location:530 – 589
      Blast Score: 200
      INCENP_ARK-bind; Inner centromere protein, ARK binding region
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AF300704.1 AAG24400.1
    genomic AC025716.2 AAK39616.1
    genomic BX284601.3 AAK39616.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9GSQ0.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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