Format

Send to:

Choose Destination

Sgk3 serum/glucocorticoid regulated kinase 3 [ Mus musculus (house mouse) ]

Gene ID: 170755, updated on 8-May-2016
Official Symbol
Sgk3provided by MGI
Official Full Name
serum/glucocorticoid regulated kinase 3provided by MGI
Primary source
MGI:MGI:2182368
See related
Ensembl:ENSMUSG00000025915
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
fy; fz; Cisk; 2510015P22Rik; A330005P07Rik
Orthologs
Location:
1 A2; 1 2.08 cM
Exon count:
19
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (9798130..9902570)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (9788211..9892651)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene valosin containing protein (p97)/p47 complex interacting protein 1 Neighboring gene RIKEN cDNA 1700034P13 gene Neighboring gene predicted gene, 39590 Neighboring gene predicted pseudogene 6195 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene minichromosome maintenance domain containing 2 Neighboring gene small nucleolar RNA, C/D box 87 Neighboring gene small nucleolar RNA host gene 6

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
fuzzy
GeneReviews: Not available

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
calcium channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
chloride channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
potassium channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
sodium channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of sodium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell growth IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic, membrane-bounded vesicle IDA
Inferred from Direct Assay
more info
PubMed 
endosome IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
serine/threonine-protein kinase Sgk3
Names
cytokine-independent survival kinase
serum/glucocorticoid-regulated kinase 3
NP_001032848.1
NP_573483.1
NP_808215.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037759.1NP_001032848.1  serine/threonine-protein kinase Sgk3

    See identical proteins and their annotated locations for NP_001032848.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC102570, AC158928, AK030314
    Consensus CDS
    CCDS14816.1
    UniProtKB/Swiss-Prot
    Q9ERE3
    Related
    ENSMUSP00000127462, OTTMUSP00000066288, ENSMUST00000171265, OTTMUST00000118862
    Conserved Domains (3) summary
    cd06870
    Location:12120
    PX_CISK; The phosphoinositide binding Phox Homology Domain of Cytokine-Independent Survival Kinase
    smart00220
    Location:162419
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05604
    Location:165490
    STKc_SGK3; Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 3
  2. NM_133220.2NP_573483.1  serine/threonine-protein kinase Sgk3

    See identical proteins and their annotated locations for NP_573483.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC102570, AC158928, AK031133, BB856423
    Consensus CDS
    CCDS14816.1
    UniProtKB/Swiss-Prot
    Q9ERE3
    Related
    ENSMUSP00000126861, OTTMUSP00000066284, ENSMUST00000168907, OTTMUST00000118856
    Conserved Domains (3) summary
    cd06870
    Location:12120
    PX_CISK; The phosphoinositide binding Phox Homology Domain of Cytokine-Independent Survival Kinase
    smart00220
    Location:162419
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05604
    Location:165490
    STKc_SGK3; Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 3
  3. NM_177547.3NP_808215.2  serine/threonine-protein kinase Sgk3

    See identical proteins and their annotated locations for NP_808215.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AC102570, AC158928, AK031133, BB856423
    Consensus CDS
    CCDS14816.1
    UniProtKB/Swiss-Prot
    Q9ERE3
    Related
    ENSMUSP00000130078, OTTMUSP00000066283, ENSMUST00000166384, OTTMUST00000118855
    Conserved Domains (3) summary
    cd06870
    Location:12120
    PX_CISK; The phosphoinositide binding Phox Homology Domain of Cytokine-Independent Survival Kinase
    smart00220
    Location:162419
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05604
    Location:165490
    STKc_SGK3; Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 3

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    9798130..9902570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    9770220..9875393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)