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Ltf lactotransferrin [ Mus musculus (house mouse) ]

Gene ID: 17002, updated on 8-May-2016
Official Symbol
Ltfprovided by MGI
Official Full Name
lactotransferrinprovided by MGI
Primary source
MGI:MGI:96837
See related
Ensembl:ENSMUSG00000032496 Vega:OTTMUSG00000052503
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lf; Csp82; Ms10r; MMS10R
Orthologs
Location:
9 60.79 cM; 9 F
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (111019292..111042766)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (110921796..110945270)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 2 Neighboring gene receptor transporter protein 3 Neighboring gene predicted gene 10030 Neighboring gene chemokine (C-C motif) receptor-like 2 Neighboring gene ribosomal protein L31, pseudogene 19

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
heparin binding ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
iron ion binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activator activity ISO
Inferred from Sequence Orthology
more info
 
serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
antibacterial humoral response ISO
Inferred from Sequence Orthology
more info
 
antifungal humoral response ISO
Inferred from Sequence Orthology
more info
 
bone morphogenesis ISO
Inferred from Sequence Orthology
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response in mucosa ISO
Inferred from Sequence Orthology
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
negative regulation by host of viral process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of ATPase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of lipopolysaccharide-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of single-species biofilm formation in or on host organism ISO
Inferred from Sequence Orthology
more info
 
negative regulation of viral genome replication ISO
Inferred from Sequence Orthology
more info
 
negative regulation of viral process ISO
Inferred from Sequence Orthology
more info
 
ossification IEA
Inferred from Electronic Annotation
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of chondrocyte proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of osteoblast proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of toll-like receptor 4 signaling pathway ISO
Inferred from Sequence Orthology
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
regulation of cytokine production ISO
Inferred from Sequence Orthology
more info
 
regulation of tumor necrosis factor production ISO
Inferred from Sequence Orthology
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
secretory granule ISO
Inferred from Sequence Orthology
more info
 
specific granule ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
lactotransferrin
Names
N lobe
lactoferrin
minisatellite 10r detected by probe MMS10
NP_032548.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008522.3NP_032548.2  lactotransferrin precursor

    See identical proteins and their annotated locations for NP_032548.2

    Status: PROVISIONAL

    Source sequence(s)
    AK036491
    Consensus CDS
    CCDS23581.1
    UniProtKB/Swiss-Prot
    P08071
    Related
    ENSMUSP00000035077, OTTMUSP00000070348, ENSMUST00000035077, OTTMUST00000131662
    Conserved Domains (4) summary
    smart00094
    Location:363692
    TR_FER; Transferrin
    pfam00405
    Location:24351
    Transferrin; Transferrin
    cd13617
    Location:361691
    PBP2_transferrin_C; The C-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    cd13618
    Location:23349
    PBP2_transferrin_N; The N-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    111019292..111042766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    110742738..110766162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)