Lmna lamin A [Mus musculus (house mouse)] - Gene

Summary

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Official Symbol: Lmnaprovided by MGI
Official Full Name: lamin Aprovided by MGI
Primary source: MGI:96794
See related: Ensembl:ENSMUSG00000028063; Vega:OTTMUSG00000030317
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Dhe
Summary: This gene encodes a protein that is a member of the lamin family. Nuclear lamins, intermediate filament-like proteins, are the major components of the nuclear lamina, a protein meshwork associated with the inner nuclear membrane. This meshwork is thought to maintain the integrity of the nuclear envelope, participate in chromatin organization, and regulate gene transcription. Vertebrate lamins consist of two types, A and B. This protein is an A-type and is proposed to be developmentally regulated. In mouse deficiency of this gene is associated with muscular dystrophy. Mouse lines with different mutations in this gene serve as pathophysiological models for several human laminopathies. In humans, mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]

Genomic context

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Location :: 3 F1; 3 38.84 cM

Sequence :: Chromosome: 3; NC_000069.6 (88481149..88503332, complement)

See Lmna in Epigenomics, MapViewer

Chromosome 3 - NC_000069.6 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Go to reference sequence details

Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study identified LBR- and lamin-A/C-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C-dependent tether.
Title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.
LMNA missense mutation caused abnormal p38alpha signaling in dilated cardiomyopathy.
Title: Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation.
Mutant lamin A/C alters the dynamics of sumo1 and thus misregulation of sumoylation may be contributing to disease progression in laminopathies.
Title: Lamin A/C mutants disturb sumo1 localization and sumoylation in vitro and in vivo.
C-terminally truncated lamin A mutant lacks protein interactions and post-translational processing.
Title: A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.
Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice
Title: Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice.
Progerin-induced changes in gene expression of lamin A-associated genes.
Title: Mapping of lamin A- and progerin-interacting genome regions.
Expression of the Hutchinson-Gilford progeria mutation in lamin A during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties
Title: Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties.
A review of the connection between LMNA mutations and hyperactivation of the extracellular signal-regulated kinase 1/2 and c-jun N-terminal kinase branches of the mitogen-activated protein kinase signaling pathway in a mouse model of dilated cardiomyopathy.
Title: Mitogen-activated protein kinase inhibitor regulation of heart function and fibrosis in cardiomyopathy caused by lamin A/C gene mutation.
The Lmna(Dhe/+) mutant mouse provides a novel model of human otitis media and laminopathy.
Title: Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies.
The results indicated that, despite the absence of a perceptible phenotype, abnormalities exist in the peripheral nerves of LmnaR298C/R298C mice that are absent from other tissues.
Title: Behavioral and molecular exploration of the AR-CMT2A mouse model Lmna (R298C/R298C).

Submit: New GeneRIF Correction See all (78)

Alleles

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Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (Floxed/Frt) (1) 1 citation
Targeted (knock-out) (6) 1 citation
Spontaneous (1) 1 citation
Targeted (other) (1) 1 citation
Targeted (knock-in) (7) 1 citation

Interactions

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Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:201176	BioGRID:197946	Actg1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:198109	Anxa3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:198208	Arpc1b	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:107506	CFTR	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:198536	Cbx3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:198538	Cbx5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:215081	Cnn3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207488	Ddx39b	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:205050	Ddx3y	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207720	Eif3i	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:199436	Emd	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:199507	Esd	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:231529	Glt25d1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:782535	Gm15032	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:240433	Gm5414	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:241504	Gm5560	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:206062	Hist1h1e	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207865	Hnrnph2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:231344	Hnrnpul1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204301	Hsp90b1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204851	Ik	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:200780	Invs	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:229985	Larp4b	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:221046	Lbr	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:237587	Lemd3	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:201177	Lmnb1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:201178	Lmnb2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:211851	Luc7l	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:213586	Mlip	BioGRID	PubMed	Affinity Capture-Western
BioGRID:201176	BioGRID:211799	Mtap	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:201650	Myh9	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207511	Nphp1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207889	Pitpnb	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:213066	Ppil1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:202421	Psmb5	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:202531	Rab10	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:208489	Rab2a	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:234840	Rab5a	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:202549	Rab5c	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:234782	Rab6b	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:202553	Rab7	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:231785	Rbm10	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:203073	Sar1a	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:203149	Sec22b	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:211777	Serbp1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:207743	Sfn	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:203557	Strap	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:218484	Sun1	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:201176	BioGRID:230179	Sun2	BioGRID	PubMed	Affinity Capture-MS; Affinity Capture-Western
BioGRID:201176	BioGRID:235364	Syne2	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:232018	Tnpo1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204276	Top2a	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:228970	Tor1aip1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204197	Trim28	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:205144	Trp53bp1	BioGRID	PubMed	Dosage Rescue
BioGRID:201176	BioGRID:204368	Ttn	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204408	Ube2i	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:199785	Xrcc6	BioGRID	PubMed	Affinity Capture-MS
BioGRID:201176	BioGRID:204620	Ywhag	BioGRID	PubMed	Affinity Capture-MS

Pathways from BioSystems

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Activation of Chaperone Genes by XBP1(S), organism-specific biosystem (from REACTOME)
Activation of Chaperone Genes by XBP1(S), organism-specific biosystemcomputationally inferred pathway (not manually curated)
Activation of Chaperones by IRE1alpha, organism-specific biosystem (from REACTOME)
Activation of Chaperones by IRE1alpha, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Adipogenesis, organism-specific biosystem (from WikiPathways)
Adipogenesis, organism-specific biosystemThe different classes of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compos...
Apoptosis, organism-specific biosystem (from REACTOME)
Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Apoptotic cleavage of cellular proteins, organism-specific biosystem (from REACTOME)
Apoptotic cleavage of cellular proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Apoptotic execution phase, organism-specific biosystem (from REACTOME)
Apoptotic execution phase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem (from KEGG)
Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystemArrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may result in arrhythmia, heart failure, and sudden death. The hallmark pathological findings are prog...
Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem (from KEGG)
Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystemArrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may result in arrhythmia, heart failure, and sudden death. The hallmark pathological findings are prog...
Breakdown of the nuclear lamina, organism-specific biosystem (from REACTOME)
Breakdown of the nuclear lamina, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cell Cycle, organism-specific biosystem (from REACTOME)
Cell Cycle, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cell Cycle, Mitotic, organism-specific biosystem (from REACTOME)
Cell Cycle, Mitotic, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Chromosome Maintenance, organism-specific biosystem (from REACTOME)
Chromosome Maintenance, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Clearance of Nuclear Envelope Membranes from Chromatin, organism-specific biosystem (from REACTOME)
Clearance of Nuclear Envelope Membranes from Chromatin, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Dilated cardiomyopathy, organism-specific biosystem (from KEGG)
Dilated cardiomyopathy, organism-specific biosystemDilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contraction of the left or both ventricles that results in progressive heart failure and sudden cardiac d...
Dilated cardiomyopathy, conserved biosystem (from KEGG)
Dilated cardiomyopathy, conserved biosystemDilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contraction of the left or both ventricles that results in progressive heart failure and sudden cardiac d...
FAS pathway and Stress induction of HSP regulation, organism-specific biosystem (from WikiPathways)
FAS pathway and Stress induction of HSP regulation, organism-specific biosystemThis pathway describes the Fas induced apoptosis and interplay with Hsp27 in response to stress. More info: [http://www.biocarta.com/pathfiles/h_hsp27Pathway.asp BioCarta].
Hypertrophic cardiomyopathy (HCM), organism-specific biosystem (from KEGG)
Hypertrophic cardiomyopathy (HCM), organism-specific biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
Hypertrophic cardiomyopathy (HCM), conserved biosystem (from KEGG)
Hypertrophic cardiomyopathy (HCM), conserved biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
Initiation of Nuclear Envelope Reformation, organism-specific biosystem (from REACTOME)
Initiation of Nuclear Envelope Reformation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
M Phase, organism-specific biosystem (from REACTOME)
M Phase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Meiosis, organism-specific biosystem (from REACTOME)
Meiosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Meiotic Synapsis, organism-specific biosystem (from REACTOME)
Meiotic Synapsis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic Anaphase, organism-specific biosystem (from REACTOME)
Mitotic Anaphase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic Metaphase and Anaphase, organism-specific biosystem (from REACTOME)
Mitotic Metaphase and Anaphase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic Prophase, organism-specific biosystem (from REACTOME)
Mitotic Prophase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Nuclear Envelope Breakdown, organism-specific biosystem (from REACTOME)
Nuclear Envelope Breakdown, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Nuclear Envelope Reassembly, organism-specific biosystem (from REACTOME)
Nuclear Envelope Reassembly, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Unfolded Protein Response, organism-specific biosystem (from REACTOME)
Unfolded Protein Response, organism-specific biosystemcomputationally inferred pathway (not manually curated)

General gene information

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Markers

MARC_3281-3282:991936958:1 (e-PCR)
- UniSTS:231005

Homology

Homologs of the Lmna gene: The Lmna gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, zebrafish, and mosquito.
Map Viewer (Human, Rat)
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
protein binding	IPI Inferred from Physical Interaction more info	PubMed
structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
establishment of cell polarity	NAS Non-traceable Author Statement more info	PubMed
establishment or maintenance of microtubule cytoskeleton polarity	IMP Inferred from Mutant Phenotype more info	PubMed
muscle organ development	ISO Inferred from Sequence Orthology more info
nuclear envelope organization	IGI Inferred from Genetic Interaction more info	PubMed
nucleus organization	IMP Inferred from Mutant Phenotype more info	PubMed
positive regulation of cell aging	ISO Inferred from Sequence Orthology more info
protein localization to nucleus	IMP Inferred from Mutant Phenotype more info	PubMed
regulation of apoptotic process	IDA Inferred from Direct Assay more info
regulation of cell migration	IMP Inferred from Mutant Phenotype more info	PubMed
sterol regulatory element binding protein import into nucleus	IMP Inferred from Mutant Phenotype more info	PubMed
ventricular cardiac muscle cell development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
cytoplasm	ISO Inferred from Sequence Orthology more info
intermediate filament	IEA Inferred from Electronic Annotation more info
lamin filament	IDA Inferred from Direct Assay more info	PubMed
nuclear envelope	IDA Inferred from Direct Assay more info
nuclear envelope	ISO Inferred from Sequence Orthology more info
nuclear matrix	ISO Inferred from Sequence Orthology more info
nucleus	IDA Inferred from Direct Assay more info	PubMed
nucleus	ISO Inferred from Sequence Orthology more info	PubMed
perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: prelamin-A/C

Names: prelamin-A/C; lamin C; lamin-A/C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002011.3 → NP_001002011.2 prelamin-A/C isoform A precursor

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (A).

Source sequence(s)

AC145168, AK004619, AK147150, AW047412

Consensus CDS

CCDS38482.1

UniProtKB/TrEMBL

B3RH23

UniProtKB/Swiss-Prot

P48678

Related

ENSMUSP00000029699, OTTMUSP00000039297, ENSMUST00000029699, OTTMUST00000075092

Conserved Domains (2) summary

pfam00038
Location:30 – 378
Blast Score: 515

Filament; Intermediate filament protein

pfam00932
Location:432 – 541
Blast Score: 205

LTD; Lamin Tail Domain
NM_001111102.2 → NP_001104572.1 prelamin-A/C isoform C

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks several 3' exons but contains an alternate 3' structure, and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (C) has a distinct and shorter C-terminus, compared to isoform A.

Source sequence(s)

AC145168, AK149998, AK210245

Consensus CDS

CCDS50951.1

UniProtKB/TrEMBL

B3RH24

UniProtKB/Swiss-Prot

P48678

UniProtKB/TrEMBL

Q3U733

UniProtKB/TrEMBL

Q3UCU3

Related

ENSMUSP00000113093, OTTMUSP00000039298, ENSMUST00000120377, OTTMUST00000075093

Conserved Domains (2) summary

pfam00038
Location:30 – 378
Blast Score: 505

Filament; Intermediate filament protein

pfam00932
Location:432 – 541
Blast Score: 206

LTD; Lamin Tail Domain
NM_019390.3 → NP_062263.1 prelamin-A/C isoform C2

Status: REVIEWED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, uses an alternate start codon, and uses an alternate 3' structure, and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (C2) has distinct N- and C-termini and is shorter than isoform A.

Source sequence(s)

AC102388, AC145168, BY140664

Consensus CDS

CCDS38483.1

UniProtKB/Swiss-Prot

P48678

Related

ENSMUSP00000040265, OTTMUSP00000039299, ENSMUST00000036252, OTTMUST00000075094

Conserved Domains (2) summary

pfam00038
Location:19 – 266
Blast Score: 324

Filament; Intermediate filament protein

pfam00932
Location:320 – 429
Blast Score: 204

LTD; Lamin Tail Domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p1 C57BL/6J

Genomic

NC_000069.6 Reference GRCm38.p1 C57BL/6J

Range

88481149..88503332, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

AC_000025.1 Alternate Mm_Celera

Range

88521102..88543289, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AAHY01028889.1 (16072..27086)	None
genomic	AAHY01028890.1 (5700..16813)	None
genomic	AC102388.7	None
genomic	AC145168.5 (57009..69439)	None
genomic	CH466547.2	EDL15275.1	mixed
		EDL15276.1	mixed
genomic	D49733.2	BAA08569.1
		BAA08570.1
		BAA08571.1
mRNA	AK003174.1	BAB22619.1	C57BL/6J
mRNA	AK004619.2	BAB23415.1	C57BL/6J
mRNA	AK079972.1	BAC37795.1	C57BL/6J
mRNA	AK147150.1	BAE27717.1	C57BL/6J
mRNA	AK149998.1	BAE29226.1	C57BL/6J
mRNA	AK150391.1	BAE29519.1	C57BL/6J
mRNA	AK150501.1	BAE29614.1	C57BL/6J
mRNA	AK150624.1	BAE29714.1	C57BL/6J
mRNA	AK152539.1	BAE31294.1	C57BL/6J
mRNA	AK152646.1	BAE31384.1	C57BL/6J
mRNA	AK152846.1	BAE31539.1	C57BL/6J
mRNA	AK153295.1	None	C57BL/6J
mRNA	AK161221.1	BAE36246.1	C57BL/6J
mRNA	AK167858.1	BAE39876.1	BALB/c
mRNA	AK179742.1	None
mRNA	AK180919.1	None
mRNA	AK182238.1	None
mRNA	AK182551.1	None
mRNA	AK182984.1	None
mRNA	AK185150.1	None
mRNA	AK186082.1	None
mRNA	AK186124.1	None
mRNA	AK186745.1	None
mRNA	AK187010.1	None
mRNA	AK188381.1	None
mRNA	AK189607.1	None
mRNA	AK189835.1	None
mRNA	AK191951.1	None
mRNA	AK192879.1	None
mRNA	AK193606.1	None
mRNA	AK194408.1	None
mRNA	AK198618.1	None
mRNA	AK200061.1	None
mRNA	AK201076.1	None
mRNA	AK201137.1	None
mRNA	AK201567.1	None
mRNA	AK203225.1	None
mRNA	AK204981.1	None
mRNA	AK205667.1	None
mRNA	AK206932.1	None
mRNA	AK208566.1	None
mRNA	AK208885.1	None
mRNA	AK210233.1	None
mRNA	AK210245.1	None
mRNA	AK211867.1	None
mRNA	AK212215.1	None
mRNA	AK215823.1	None
mRNA	AK216120.1	None
mRNA	AK216537.1	None
mRNA	AK217160.1	None
mRNA	AK217904.1	None
mRNA	AK218054.1	None
mRNA	AK218088.1	None
mRNA	AK218995.1	None
mRNA	AW047412.1	None	C57BL/6J
mRNA	BC015302.1	AAH15302.1	FVB/N
mRNA	BC094020.1	AAH94020.1	FVB/N
mRNA	BQ715532.1	None
mRNA	BY140664.1	None	C57BL/6J
mRNA	D13181.1	BAA02476.1	C3H/He
mRNA	D14850.1	BAA03578.1	DDY
mRNA	DQ832702.1	ABI16251.1
mRNA	DQ832703.1	ABI16252.1
mRNA	X14170.1	CAA32372.1