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Krt8 keratin 8 [ Mus musculus (house mouse) ]

Gene ID: 16691, updated on 29-May-2016
Official Symbol
Krt8provided by MGI
Official Full Name
keratin 8provided by MGI
Primary source
MGI:MGI:96705
See related
Ensembl:ENSMUSG00000049382
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K8; Card2; EndoA; Krt2-8; Krt-2.8; AA960620; AL022697; AU019895
Orthologs
Location:
15 F3; 15 57.2 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (101996711..102004342, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101827142..101834773, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene keratin 79 Neighboring gene keratin 78 Neighboring gene predicted gene, 36026 Neighboring gene predicted gene, 41404

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC118110

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell differentiation involved in embryonic placenta development IGI
Inferred from Genetic Interaction
more info
PubMed 
cell morphogenesis involved in differentiation TAS
Traceable Author Statement
more info
PubMed 
extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
hepatocyte apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development TAS
Traceable Author Statement
more info
PubMed 
response to hydrostatic pressure ISO
Inferred from Sequence Orthology
more info
 
response to other organism IMP
Inferred from Mutant Phenotype
more info
PubMed 
sarcomere organization ISO
Inferred from Sequence Orthology
more info
 
tumor necrosis factor-mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
tumor necrosis factor-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
Z disc ISO
Inferred from Sequence Orthology
more info
 
cell periphery IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
costamere ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
dystrophin-associated glycoprotein complex ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intermediate filament IDA
Inferred from Direct Assay
more info
PubMed 
intermediate filament ISO
Inferred from Sequence Orthology
more info
 
keratin filament ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
sarcolemma ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
keratin, type II cytoskeletal 8
Names
CK-8
cytokeratin 8
cytokeratin endo A
cytokeratin-8
keratin complex 2, basic, gene 8
keratin-8
type-II keratin Kb8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031170.2NP_112447.2  keratin, type II cytoskeletal 8

    See identical proteins and their annotated locations for NP_112447.2

    Status: VALIDATED

    Source sequence(s)
    AK145777
    Consensus CDS
    CCDS27868.1
    UniProtKB/Swiss-Prot
    P11679
    Related
    ENSMUSP00000023952, ENSMUST00000023952
    Conserved Domains (2) summary
    pfam00038
    Location:96407
    Filament; Intermediate filament protein
    pfam15003
    Location:285382
    HAUS2; HAUS augmin-like complex subunit 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    101996711..102004342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    104151508..104159109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)