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RBM46 RNA binding motif protein 46 [ Homo sapiens (human) ]

Gene ID: 166863, updated on 26-May-2016
Official Symbol
RBM46provided by HGNC
Official Full Name
RNA binding motif protein 46provided by HGNC
Primary source
HGNC:HGNC:28401
See related
Ensembl:ENSG00000151962 HPRD:14517; Vega:OTTHUMG00000161543
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT68
Orthologs
Location:
4q32.1
Exon count:
11
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 4 NC_000004.12 (154781252..154828813)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (155702424..155749965)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene fibrinogen gamma chain Neighboring gene lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) Neighboring gene uncharacterized LOC105377500 Neighboring gene uncharacterized LOC105377501 Neighboring gene neuropeptide Y receptor Y2

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC27016

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
probable RNA-binding protein 46
Names
RNA-binding motif protein 46
cancer/testis antigen 68

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277171.1NP_001264100.1  probable RNA-binding protein 46 isoform 2

    See identical proteins and their annotated locations for NP_001264100.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an additional exon that results in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AK125877, AK302720, BC028588, DB449155
    Consensus CDS
    CCDS64085.1
    UniProtKB/Swiss-Prot
    Q8TBY0
    Related
    ENSP00000424500, OTTHUMP00000220358, ENST00000514866, OTTHUMT00000365258
    Conserved Domains (5) summary
    smart00360
    Location:63134
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  2. NM_001277173.1NP_001264102.1  probable RNA-binding protein 46 isoform 3

    See identical proteins and their annotated locations for NP_001264102.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, and uses an alternate 3' terminal exon that results in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AK125877, BC028588
    Consensus CDS
    CCDS64086.1
    UniProtKB/Swiss-Prot
    Q8TBY0
    Related
    ENSP00000422813, OTTHUMP00000220357, ENST00000510397, OTTHUMT00000365257
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  3. NM_144979.4NP_659416.1  probable RNA-binding protein 46 isoform 1

    See identical proteins and their annotated locations for NP_659416.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    BC028588, DB449155, DB527978
    Consensus CDS
    CCDS3790.1
    UniProtKB/Swiss-Prot
    Q8TBY0
    Related
    ENSP00000281722, OTTHUMP00000220359, ENST00000281722, OTTHUMT00000365259
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p2 Primary Assembly

    Range
    154781252..154828813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531695.1XP_011529997.1  

    See identical proteins and their annotated locations for XP_011529997.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  2. XM_006714120.1XP_006714183.1  

    See identical proteins and their annotated locations for XP_006714183.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  3. XM_006714119.2XP_006714182.1  

    See identical proteins and their annotated locations for XP_006714182.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:63134
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  4. XM_011531697.1XP_011529999.1  

    Conserved Domains (5) summary
    smart00360
    Location:63134
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393463
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  5. XM_011531693.1XP_011529995.1  

    See identical proteins and their annotated locations for XP_011529995.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  6. XM_011531692.1XP_011529994.1  

    See identical proteins and their annotated locations for XP_011529994.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  7. XM_011531694.1XP_011529996.1  

    See identical proteins and their annotated locations for XP_011529996.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
  8. XM_011531696.1XP_011529998.1  

    See identical proteins and their annotated locations for XP_011529998.1

    UniProtKB/Swiss-Prot
    Q8TBY0
    Conserved Domains (5) summary
    smart00360
    Location:237303
    RRM; RNA recognition motif
    cd12484
    Location:60137
    RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12492
    Location:139223
    RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
    cd12496
    Location:235308
    RRM3_RBM46; RNA recognition motif 3 in vertebrate RNA-binding protein 46 (RBM46)
    pfam14709
    Location:393468
    DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1

Alternate CHM1_1.1

Genomic

  1. NC_018915.2 Alternate CHM1_1.1

    Range
    155680305..155727841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)