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Krt4 keratin 4 [ Mus musculus (house mouse) ]

Gene ID: 16682, updated on 28-May-2016
Official Symbol
Krt4provided by MGI
Official Full Name
keratin 4provided by MGI
Primary source
MGI:MGI:96701
See related
Ensembl:ENSMUSG00000059668
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K4; Krt2-4; Krt-2.4; AW108092
Location:
15 F3; 15 57.13 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (101918535..101924735, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101748966..101755166, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene keratin 77 Neighboring gene keratin 76 Neighboring gene keratin 79 Neighboring gene keratin 78

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein heterodimerization activity TAS
Traceable Author Statement
more info
PubMed 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
embryo development TAS
Traceable Author Statement
more info
PubMed 
epithelial cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
intermediate filament IEA
Inferred from Electronic Annotation
more info
 
intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
keratin filament ISO
Inferred from Sequence Orthology
more info
 
keratin filament TAS
Traceable Author Statement
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
keratin, type II cytoskeletal 4
Names
57kDa keratin
57kd keratin
CK-4
cytokeratin-4
cytoskeletal 57 kDa keratin
keratin complex 2, basic, gene 4
keratin-4
type-II keratin Kb4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008475.2NP_032501.2  keratin, type II cytoskeletal 4

    See identical proteins and their annotated locations for NP_032501.2

    Status: VALIDATED

    Source sequence(s)
    BC064008, BY139439
    Consensus CDS
    CCDS37222.1
    UniProtKB/Swiss-Prot
    P07744
    Related
    ENSMUSP00000023797, ENSMUST00000023797
    Conserved Domains (3) summary
    pfam00038
    Location:146458
    Filament; Intermediate filament protein
    cl18042
    Location:201277
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    cl19517
    Location:351434
    DivIVA; DivIVA protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    101918535..101924735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    104070333..104076533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)