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Krt18 keratin 18 [ Mus musculus (house mouse) ]

Gene ID: 16668, updated on 8-May-2016
Official Symbol
Krt18provided by MGI
Official Full Name
keratin 18provided by MGI
Primary source
MGI:MGI:96692
See related
Ensembl:ENSMUSG00000023043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K18; CK18; Krt1-18
Orthologs
Location:
15 F3; 15 57.22 cM
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (102028216..102032026)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101858647..101862457)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36026 Neighboring gene predicted gene, 41404 Neighboring gene predicted gene, 41405 Neighboring gene eukaryotic translation initiation factor 4B

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Golgi to plasma membrane CFTR protein transport ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
hepatocyte apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
intermediate filament cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
tumor necrosis factor-mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cell periphery IDA
Inferred from Direct Assay
more info
PubMed 
centriolar satellite ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intermediate filament IDA
Inferred from Direct Assay
more info
PubMed 
intermediate filament ISO
Inferred from Sequence Orthology
more info
 
keratin filament IDA
Inferred from Direct Assay
more info
PubMed 
keratin filament ISO
Inferred from Sequence Orthology
more info
 
microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
keratin, type I cytoskeletal 18
Names
cytokeratin endo B
cytokeratin-18
keratin D
keratin complex 1, acidic, gene 18

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010664.2NP_034794.2  keratin, type I cytoskeletal 18

    See identical proteins and their annotated locations for NP_034794.2

    Status: VALIDATED

    Source sequence(s)
    AK167469, AW539037, CV561123
    Consensus CDS
    CCDS27869.1
    UniProtKB/Swiss-Prot
    P05784
    Related
    ENSMUSP00000023803, ENSMUST00000023803
    Conserved Domains (1) summary
    pfam00038
    Location:72382
    Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    102028216..102032026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    104183109..104186912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)