These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001040260.3 → NP_001035350.2 serine/threonine-protein kinase DCLK2 isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) is known as exon-5-lacking transcript (PMIDs:15611072 and 18075264). It lacks an in-frame coding exon in the 5' region, as compared to variant 2. The resulting isoform (a) lacks an internal segment, as compared to isoform b.
- Source sequence(s)
-
AB209181, AC093748, AI419589, DA122884
- Consensus CDS
-
CCDS34076.1
- UniProtKB/Swiss-Prot
-
Q8N568
- Related
- ENSP00000296550, OTTHUMP00000220237, ENST00000296550, OTTHUMT00000364952
- Conserved Domains (3) summary
-
- cd01617
Location:72 – 154
Blast Score: 295
- DCX; Ubiquitin-like domain of DCX
- smart00220
Location:394 – 651
Blast Score: 805
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl09925
Location:394 – 653
Blast Score: 575
- PKc_like; Protein Kinases, catalytic domain
-
NM_001040261.4 → NP_001035351.4 serine/threonine-protein kinase DCLK2 isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is known as exon-5-containing transcript (PMIDs:15611072 and 18075264) and encodes the longer isoform (b).
- Source sequence(s)
-
AC093748, AC105343, AL834498
- Consensus CDS
-
CCDS47142.2
- UniProtKB/Swiss-Prot
-
Q8N568
- Related
- ENSP00000303887, OTTHUMP00000220239, ENST00000302176, OTTHUMT00000364954
- Conserved Domains (3) summary
-
- cd01617
Location:72 – 154
Blast Score: 295
- DCX; Ubiquitin-like domain of DCX
- smart00220
Location:411 – 668
Blast Score: 807
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl09925
Location:411 – 670
Blast Score: 576
- PKc_like; Protein Kinases, catalytic domain
RNA
-
NR_036614.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) is known as exon-17/16-containing transcript (PMIDs:15611072 and 18075264). It has an alternate splice site in the middle region, resulting in 3 nts missing, and has an additional exon in the 3' region, which includes a translation stop codon and results in a nonsense-mediated mRNA decay candidate, as compared to variant 2. This transcript is developmentally regulated and most probably does not make a protein.
- Source sequence(s)
-
AC093748, AC105343, BC032726
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000004.11 Reference GRCh37.p5 Primary Assembly
- Range
- 150999426..151178609
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000136.1 Alternate HuRef
- Range
- 146722453..146904055
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_152619.1: Suppressed sequence
- Description
- NM_152619.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.