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Kpna4 karyopherin (importin) alpha 4 [ Mus musculus (house mouse) ]

Gene ID: 16649, updated on 28-May-2016
Official Symbol
Kpna4provided by MGI
Official Full Name
karyopherin (importin) alpha 4provided by MGI
Primary source
MGI:MGI:1100848
See related
Ensembl:ENSMUSG00000027782
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IPOA3; 1110058D08Rik
Orthologs
Location:
3; 3 E2
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (69072221..69127092, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (68876143..68931014, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 59 Neighboring gene uncharacterized LOC105244467 Neighboring gene predicted gene 1647 Neighboring gene ADP-ribosylation factor-like 14

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
NLS-bearing protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
protein import into nucleus IDA
Inferred from Direct Assay
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
response to hydrogen peroxide IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
importin subunit alpha-3
Names
importin alpha 3
importin alpha Q1
importin subunit alpha-4
karyopherin subunit alpha-4
qip1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008467.4NP_032493.1  importin subunit alpha-3

    See identical proteins and their annotated locations for NP_032493.1

    Status: PROVISIONAL

    Source sequence(s)
    AC119847
    Consensus CDS
    CCDS17403.1
    UniProtKB/Swiss-Prot
    O35343
    UniProtKB/TrEMBL
    Q4FJX1
    Related
    ENSMUSP00000141227, ENSMUST00000194558
    Conserved Domains (3) summary
    pfam01749
    Location:394
    IBB; Importin beta binding domain
    COG5064
    Location:11513
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    cd00020
    Location:108229
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    69072221..69127092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    69178407..69233653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)