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Kpna2 karyopherin (importin) alpha 2 [ Mus musculus (house mouse) ]

Gene ID: 16647, updated on 8-May-2016
Official Symbol
Kpna2provided by MGI
Official Full Name
karyopherin (importin) alpha 2provided by MGI
Primary source
MGI:MGI:103561
See related
Ensembl:ENSMUSG00000018362 Vega:OTTMUSG00000003580
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rch1; IPOA1; PTAC58; 2410044B12Rik
Orthologs
Location:
11; 11 E1
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (106988629..106999525, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (106849943..106860839, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene Smad nuclear interacting protein 1 pseudogene Neighboring gene mediator of cell motility 1 pseudogene Neighboring gene nuclear encoded tRNA arginine 1 (anticodon CCG) Neighboring gene predicted gene, 39424

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC91246

Gene Ontology Provided by MGI

Function Evidence Code Pubs
histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
 
nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear localization sequence binding ISO
Inferred from Sequence Orthology
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
NLS-bearing protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
NLS-bearing protein import into nucleus ISO
Inferred from Sequence Orthology
more info
 
protein import into nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
importin subunit alpha-1
Names
RAG cohort protein 1
SRP1-alpha
importin alpha 1
importin alpha P1
importin subunit alpha-2
karyopherin subunit alpha-2
m-importin-alpha-P1
pendulin
pore targeting complex 58 kDa subunit

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010655.3NP_034785.1  importin subunit alpha-1

    See identical proteins and their annotated locations for NP_034785.1

    Status: VALIDATED

    Source sequence(s)
    AI664586, AK075952, BC086789
    Consensus CDS
    CCDS25565.1
    UniProtKB/Swiss-Prot
    P52293
    UniProtKB/TrEMBL
    Q52L97
    Related
    ENSMUSP00000018506, OTTMUSP00000003739, ENSMUST00000018506, OTTMUST00000007708
    Conserved Domains (3) summary
    pfam01749
    Location:599
    IBB; Importin beta binding domain
    COG5064
    Location:9528
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    cd00020
    Location:113238
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    106988629..106999525 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    118719792..118733297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)