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Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 [ Mus musculus (house mouse) ]

Gene ID: 16516, updated on 8-May-2016
Official Symbol
Kcnj15provided by MGI
Official Full Name
potassium inwardly-rectifying channel, subfamily J, member 15provided by MGI
Primary source
MGI:MGI:1310000
See related
Ensembl:ENSMUSG00000062609 Vega:OTTMUSG00000019964
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IRKK; Kir4.2; AI182284; AI267127; 4930414N08Rik
Orthologs
Location:
16 C4; 16 55.86 cM
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (95257558..95300260)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (95479258..95521867)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31407 Neighboring gene predicted gene, 31641 Neighboring gene predicted gene, 31754 Neighboring gene avian erythroblastosis virus E-26 (v-ets) oncogene related Neighboring gene predicted gene, 31845

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
inward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
inward rectifier potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ion transport IEA
Inferred from Electronic Annotation
more info
 
potassium ion import IBA
Inferred from Biological aspect of Ancestor
more info
 
potassium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IC
Inferred by Curator
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ATP-sensitive inward rectifier potassium channel 15
Names
inward rectifier K+ channel Kir4.2
potassium channel, inwardly rectifying subfamily J member 15

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039056.2NP_001034145.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001034145.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Related
    ENSMUSP00000109485, OTTMUSP00000021538, ENSMUST00000113854, OTTMUST00000047571
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  2. NM_001039057.2NP_001034146.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001034146.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AI116801, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    Q3TNE6, Q53Z04
    Related
    ENSMUSP00000045218, OTTMUSP00000021537, ENSMUST00000037154, OTTMUST00000047570
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  3. NM_001271687.1NP_001258616.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258616.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AI891955, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    Q3TNE6, Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  4. NM_001271689.1NP_001258618.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258618.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154546, AC154691
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Related
    ENSMUSP00000109486, OTTMUSP00000021539, ENSMUST00000113855, OTTMUST00000047572
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  5. NM_001271690.1NP_001258619.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258619.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AK165346, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    Q3TNE6, Q53Z04
    Related
    ENSMUSP00000109492, OTTMUSP00000021535, ENSMUST00000113861, OTTMUST00000047568
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  6. NM_001271691.1NP_001258620.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258620.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW012236
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  7. NM_001271692.1NP_001258621.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258621.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154546, AC154691
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    Q3TNE6
    Related
    ENSMUSP00000109490, OTTMUSP00000021540, ENSMUST00000113859, OTTMUST00000047573
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  8. NM_001271693.1NP_001258622.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258622.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW258994, AY377988
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  9. NM_001271694.1NP_001258623.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258623.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AK165436, AW319416
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    Q3TNE6, Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  10. NM_001271695.1NP_001258624.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258624.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AI891955, AK165436, BB843850
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  11. NM_019664.5NP_062638.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_062638.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW260030, AY377988
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Related
    ENSMUSP00000109487, ENSMUST00000113856
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel

RNA

  1. NR_073406.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) uses an alternate splice site and two alternate internal exons, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC154546, AC154691

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    95257558..95300260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522944.2XP_006523007.1  

    See identical proteins and their annotated locations for XP_006523007.1

    UniProtKB/TrEMBL
    Q3TNE6
    Related
    ENSMUSP00000109493, OTTMUSP00000021534, ENSMUST00000113862, OTTMUST00000047567
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  2. XM_006522942.2XP_006523005.1  

    See identical proteins and their annotated locations for XP_006523005.1

    UniProtKB/TrEMBL
    Q3TNE6
    Related
    ENSMUSP00000109489, OTTMUSP00000021536, ENSMUST00000113858, OTTMUST00000047569
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  3. XM_006522945.2XP_006523008.1  

    See identical proteins and their annotated locations for XP_006523008.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  4. XM_006522951.2XP_006523014.1  

    See identical proteins and their annotated locations for XP_006523014.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  5. XM_006522950.2XP_006523013.1  

    See identical proteins and their annotated locations for XP_006523013.1

    Conserved Domains (1) summary
    pfam01007
    Location:46381
    IRK; Inward rectifier potassium channel
  6. XM_006522949.2XP_006523012.1  

    See identical proteins and their annotated locations for XP_006523012.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  7. XM_006522947.2XP_006523010.1  

    See identical proteins and their annotated locations for XP_006523010.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  8. XM_006522946.2XP_006523009.1  

    See identical proteins and their annotated locations for XP_006523009.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  9. XM_006522952.2XP_006523015.1  

    See identical proteins and their annotated locations for XP_006523015.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel

Reference GRCm38.p3 129S6/SvEvTac

Genomic

  1. NT_039634.4 Reference GRCm38.p3 129S6/SvEvTac

    Range
    1129150..1171703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523175.2XP_006523238.1  

    See identical proteins and their annotated locations for XP_006523238.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  2. XM_006523188.2XP_006523251.1  

    See identical proteins and their annotated locations for XP_006523251.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  3. XM_006523177.2XP_006523240.1  

    See identical proteins and their annotated locations for XP_006523240.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  4. XM_006523187.2XP_006523250.1  

    See identical proteins and their annotated locations for XP_006523250.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  5. XM_006523174.2XP_006523237.1  

    See identical proteins and their annotated locations for XP_006523237.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  6. XM_006523176.2XP_006523239.1  

    See identical proteins and their annotated locations for XP_006523239.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  7. XM_006523190.2XP_006523253.1  

    See identical proteins and their annotated locations for XP_006523253.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  8. XM_006523189.2XP_006523252.1  

    See identical proteins and their annotated locations for XP_006523252.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  9. XM_006523178.2XP_006523241.1  

    See identical proteins and their annotated locations for XP_006523241.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  10. XM_006523180.2XP_006523243.1  

    See identical proteins and their annotated locations for XP_006523243.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  11. XM_006523191.2XP_006523254.1  

    See identical proteins and their annotated locations for XP_006523254.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  12. XM_006523186.2XP_006523249.1  

    See identical proteins and their annotated locations for XP_006523249.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  13. XM_006523173.2XP_006523236.1  

    See identical proteins and their annotated locations for XP_006523236.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  14. XM_006523185.2XP_006523248.1  

    See identical proteins and their annotated locations for XP_006523248.1

    Conserved Domains (1) summary
    pfam01007
    Location:46381
    IRK; Inward rectifier potassium channel
  15. XM_006523192.2XP_006523255.1  

    See identical proteins and their annotated locations for XP_006523255.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel
  16. XM_006523179.2XP_006523242.1  

    See identical proteins and their annotated locations for XP_006523242.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  17. XM_006523184.2XP_006523247.1  

    See identical proteins and their annotated locations for XP_006523247.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  18. XM_006523182.2XP_006523245.1  

    See identical proteins and their annotated locations for XP_006523245.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  19. XM_006523181.2XP_006523244.1  

    See identical proteins and their annotated locations for XP_006523244.1

    UniProtKB/TrEMBL
    Q3TNE6
    Conserved Domains (1) summary
    pfam01007
    Location:57392
    IRK; Inward rectifier potassium channel
  20. XM_006523193.2XP_006523256.1  

    See identical proteins and their annotated locations for XP_006523256.1

    UniProtKB/Swiss-Prot
    O88932
    UniProtKB/TrEMBL
    Q53Z04
    Conserved Domains (1) summary
    pfam01007
    Location:30365
    IRK; Inward rectifier potassium channel

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    96348273..96378516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. NW_001072430.1 Alternate Mm_Celera

    Range
    14812..15570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)