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Ajuba ajuba LIM protein [ Mus musculus (house mouse) ]

Gene ID: 16475, updated on 8-May-2016
Official Symbol
Ajubaprovided by MGI
Official Full Name
ajuba LIM proteinprovided by MGI
Primary source
MGI:MGI:1341886
See related
Ensembl:ENSMUSG00000022178
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Jub
Orthologs
Location:
14; 14 C3
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 14 NC_000080.6 (54567469..54577661, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55186309..55196253, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41157 Neighboring gene HAUS augmin-like complex, subunit 4 Neighboring gene RIKEN cDNA 4931414P19 gene Neighboring gene proteasome (prosome, macropain) subunit, beta type 5 Neighboring gene microRNA 686

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin filament binding IDA
Inferred from Direct Assay
more info
PubMed 
alpha-catenin binding IDA
Inferred from Direct Assay
more info
PubMed 
alpha-catenin binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription corepressor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cellular protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
focal adhesion assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
gene silencing by RNA IEA
Inferred from Electronic Annotation
more info
 
gene silencing by miRNA ISO
Inferred from Sequence Orthology
more info
 
glycerophospholipid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
lamellipodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of hippo signaling ISO
Inferred from Sequence Orthology
more info
 
negative regulation of kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of MAP kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cellular biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gene silencing by miRNA ISO
Inferred from Sequence Orthology
more info
 
positive regulation of kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of protein complex assembly ISO
Inferred from Sequence Orthology
more info
 
regulation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell migration IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
wound healing, spreading of epidermal cells IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic mRNA processing body ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
transcription factor complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
LIM domain-containing protein ajuba
Names
protein ajuba

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010590.5NP_034720.2  LIM domain-containing protein ajuba

    See identical proteins and their annotated locations for NP_034720.2

    Status: VALIDATED

    Source sequence(s)
    AC164433
    Consensus CDS
    CCDS27093.1
    UniProtKB/Swiss-Prot
    Q91XC0
    Related
    ENSMUSP00000056977, ENSMUST00000054487
    Conserved Domains (3) summary
    cd09352
    Location:347400
    LIM1_Ajuba_like; The first LIM domain of Ajuba-like proteins
    cd09355
    Location:412464
    LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
    cd09438
    Location:472533
    LIM3_Ajuba_like; The third LIM domain of Ajuba-like proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p3 C57BL/6J

    Range
    54567469..54577661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000036.1 Alternate Mm_Celera

    Range
    52356264..52366595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)