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Itsn1 intersectin 1 (SH3 domain protein 1A) [ Mus musculus (house mouse) ]

Gene ID: 16443, updated on 8-May-2016
Official Symbol
Itsn1provided by MGI
Official Full Name
intersectin 1 (SH3 domain protein 1A)provided by MGI
Primary source
MGI:MGI:1338069
See related
Ensembl:ENSMUSG00000022957 Vega:OTTMUSG00000021345
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ese1; Itsn; Ehsh1; Sh3p17; AA517634; AA545208; AI316805; AI839402; AI848451
Orthologs
Location:
16; 16 C3.3-C4
Exon count:
45
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (91729354..91920591)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (91729616..91920824)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene Son DNA binding protein Neighboring gene downstream neighbor of SON Neighboring gene predicted gene 10785 Neighboring gene crystallin, zeta (quinone reductase)-like 1 Neighboring gene RIKEN cDNA D430001F17 gene Neighboring gene ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit Neighboring gene predicted gene, 36797

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
Rho guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
proline-rich region binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex scaffold ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
endocytosis IEA
Inferred from Electronic Annotation
more info
 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein kinase B signaling IDA
Inferred from Direct Assay
more info
PubMed 
regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
small GTPase mediated signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
coated pit ISO
Inferred from Sequence Orthology
more info
 
endocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
intersectin-1
Names
EH and SH3 domains protein 1
Eh domain, SH3 domain regulator of endocytosis 1
intersectin (SH3 domain protein 1A)
intersectin short form 2 variant 2
intersectin-L

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110275.1NP_001103745.1  intersectin-1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences in the presence and absence of exons at its 3' end, compared to variant 1. These differences produce a unique 3' UTR and result in a protein (isoform 2) that is shorter at the C-terminus, compared to isoform 1.
    Source sequence(s)
    AF132478, BC062938
    Consensus CDS
    CCDS49913.1
    UniProtKB/Swiss-Prot
    Q9Z0R4
    Related
    ENSMUSP00000056011, OTTMUSP00000023654, ENSMUST00000056482, OTTMUST00000050609
    Conserved Domains (9) summary
    smart00027
    Location:214309
    EH; Eps15 homology domain
    cd11987
    Location:742796
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:9991050
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:11511204
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:351465
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:350646
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:225291
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:577666
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:10671131
    SH3; Src Homology 3 domain superfamily
  2. NM_001110276.1NP_001103746.1  intersectin-1 isoform 3

    See identical proteins and their annotated locations for NP_001103746.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences in the presence and absence of exons at its 3' end, compared to variant 1. These differences produce a unique 3' UTR and result in a shorter protein (isoform 3) with a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC066105, CB519152
    Consensus CDS
    CCDS49914.1
    UniProtKB/TrEMBL
    Q6NZJ5
    Related
    ENSMUSP00000093598, OTTMUSP00000023653, ENSMUST00000095909, OTTMUST00000050608
    Conserved Domains (3) summary
    smart00027
    Location:214309
    EH; Eps15 homology domain
    cl17108
    Location:351465
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    cd00052
    Location:225291
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
  3. NM_010587.2NP_034717.2  intersectin-1 isoform 1

    See identical proteins and their annotated locations for NP_034717.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC126053, AF132481, AK082606, BC062938
    Consensus CDS
    CCDS37402.1
    UniProtKB/Swiss-Prot
    Q9Z0R4
    UniProtKB/TrEMBL
    Q8C4B5
    Related
    ENSMUSP00000109635, OTTMUSP00000023652, ENSMUST00000114002, OTTMUST00000050607
    Conserved Domains (13) summary
    cd08375
    Location:15751709
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:214309
    EH; Eps15 homology domain
    cd11987
    Location:742796
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11989
    Location:910961
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11991
    Location:9991050
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:10671131
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:11511204
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:351465
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:350646
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:225291
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:12311414
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:577666
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:14411572
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    91729354..91920591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522934.2XP_006522997.1  

    UniProtKB/TrEMBL
    E9Q0N0
    Related
    ENSMUSP00000066361, OTTMUSP00000023658, ENSMUST00000064797, OTTMUST00000050614
    Conserved Domains (13) summary
    cd08375
    Location:15801714
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:214309
    EH; Eps15 homology domain
    cd11989
    Location:915966
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11991
    Location:10041055
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:10721136
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:11561209
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:351465
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:350646
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:225291
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:12361419
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:577666
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:14461577
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:742801
    SH3; Src Homology 3 domain superfamily
  2. XM_006522931.1XP_006522994.1  

    Conserved Domains (13) summary
    cd08375
    Location:16041738
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11989
    Location:939990
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11991
    Location:10281079
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:10961160
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:11801233
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:12601443
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:14701601
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:766825
    SH3; Src Homology 3 domain superfamily
  3. XM_006522935.1XP_006522998.1  

    Conserved Domains (12) summary
    cd08375
    Location:15331667
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11987
    Location:766825
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11989
    Location:939990
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11995
    Location:11091162
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:11891372
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:13991530
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:10281089
    SH3; Src Homology 3 domain superfamily
  4. XM_006522933.1XP_006522996.1  

    Conserved Domains (13) summary
    cd08375
    Location:15991733
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11987
    Location:766820
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11989
    Location:934985
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11991
    Location:10231074
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:10911155
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:11751228
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:12551438
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:14651596
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
  5. XM_006522936.1XP_006522999.1  

    Conserved Domains (12) summary
    cd08375
    Location:15281662
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11987
    Location:766820
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11989
    Location:934985
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11995
    Location:11041157
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:11841367
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:13941525
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:10231084
    SH3; Src Homology 3 domain superfamily
  6. XM_006522938.1XP_006523001.1  

    Conserved Domains (8) summary
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11991
    Location:10281079
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:11801233
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:10961160
    SH3; Src Homology 3 domain superfamily
  7. XM_006522939.1XP_006523002.1  

    Conserved Domains (9) summary
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cd11987
    Location:766820
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:10231074
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:11751228
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:10911155
    SH3; Src Homology 3 domain superfamily
  8. XM_011246102.1XP_011244404.1  

    See identical proteins and their annotated locations for XP_011244404.1

    Conserved Domains (6) summary
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:766825
    SH3; Src Homology 3 domain superfamily
  9. XM_011246101.1XP_011244403.1  

    See identical proteins and their annotated locations for XP_011244403.1

    Conserved Domains (6) summary
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:766825
    SH3; Src Homology 3 domain superfamily
  10. XM_006522940.1XP_006523003.1  

    Conserved Domains (6) summary
    smart00027
    Location:238333
    EH; Eps15 homology domain
    cl17108
    Location:375489
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:374670
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:249315
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam03938
    Location:601690
    OmpH; Outer membrane protein (OmpH-like)
    cl17036
    Location:766825
    SH3; Src Homology 3 domain superfamily
  11. XM_006522932.2XP_006522995.1  

    Conserved Domains (13) summary
    cd08375
    Location:16021736
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:236331
    EH; Eps15 homology domain
    cd11989
    Location:937988
    SH3_Intersectin1_2; Second Src homology 3 domain (or SH3B) of Intersectin-1
    cd11991
    Location:10261077
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:10941158
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:11781231
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:373487
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:372668
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:247313
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:12581441
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:599688
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:14681599
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:764823
    SH3; Src Homology 3 domain superfamily
  12. XM_006522937.2XP_006523000.1  

    Conserved Domains (12) summary
    cd08375
    Location:13871521
    C2_Intersectin; C2 domain present in Intersectin
    smart00027
    Location:21116
    EH; Eps15 homology domain
    cd11991
    Location:811862
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11993
    Location:879943
    SH3_Intersectin1_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-1
    cd11995
    Location:9631016
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    cl17108
    Location:158272
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
    COG1340
    Location:157453
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00052
    Location:3298
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    cd00160
    Location:10431226
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    pfam03938
    Location:384473
    OmpH; Outer membrane protein (OmpH-like)
    cd13264
    Location:12531384
    PH_ITSN; Intersectin Pleckstrin homology (PH) domain
    cl17036
    Location:549608
    SH3; Src Homology 3 domain superfamily

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    92808009..93004876
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)