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Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [ Mus musculus (house mouse) ]

Gene ID: 16434, updated on 28-May-2016
Official Symbol
Itpaprovided by MGI
Official Full Name
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)provided by MGI
Primary source
MGI:MGI:96622
See related
Ensembl:ENSMUSG00000074797 Vega:OTTMUSG00000015497
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Itp; AU020102; 2010016I08Rik
Orthologs
Location:
2 F1; 2 63.24 cM
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (130667841..130681614)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (130493577..130507350)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene leucine zipper, putative tumor suppressor family member 3 Neighboring gene DDRGK domain containing 1 Neighboring gene predicted gene, 30229 Neighboring gene solute carrier family 4, sodium bicarbonate transporter-like, member 11 Neighboring gene RIKEN cDNA 4930402H24 gene Neighboring gene chaperonin containing Tcp1, subunit 3 (gamma) pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ITP diphosphatase activity ISO
Inferred from Sequence Orthology
more info
 
XTP diphosphatase activity ISO
Inferred from Sequence Orthology
more info
 
dITP diphosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
dITP diphosphatase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleoside-triphosphate diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ITP catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleoside triphosphate catabolic process IEA
Inferred from Electronic Annotation
more info
 
nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
inosine triphosphate pyrophosphatase
Names
ITPase
NTPase
non-canonical purine NTP pyrophosphatase
non-standard purine NTP pyrophosphatase
nucleoside triphosphate pyrophosphatase
nucleoside-triphosphate diphosphatase
nucleoside-triphosphate pyrophosphatase
NP_080198.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025922.2NP_080198.2  inosine triphosphate pyrophosphatase

    See identical proteins and their annotated locations for NP_080198.2

    Status: PROVISIONAL

    Source sequence(s)
    BC026508
    Consensus CDS
    CCDS16748.1
    UniProtKB/Swiss-Prot
    Q9D892
    UniProtKB/TrEMBL
    Q60I30
    Related
    ENSMUSP00000099482, OTTMUSP00000016511, ENSMUST00000103193, OTTMUST00000036804
    Conserved Domains (1) summary
    cd00515
    Location:10188
    HAM1; NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    130667841..130681614
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    131892647..131906412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)