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Itgb6 integrin beta 6 [ Mus musculus (house mouse) ]

Gene ID: 16420, updated on 26-Jun-2015
Official Symbol
Itgb6provided by MGI
Official Full Name
integrin beta 6provided by MGI
Primary source
MGI:MGI:96615
See related
Ensembl:ENSMUSG00000026971; Vega:OTTMUSG00000012790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210409C20Rik; 4831415H04Rik
Orthologs
See Itgb6 in Epigenomics, MapViewer
Location:
2 34.81 cM; 2 C3
Exon count:
21
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (60598292..60722603, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (60436349..60560660, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S21 pseudogene Neighboring gene TBC1 domain family, member 15 pseudogene Neighboring gene predicted gene, 33436 Neighboring gene RNA binding motif, single stranded interacting protein 1 Neighboring gene predicted gene, 33598 Neighboring gene predicted gene 13582 Neighboring gene predicted gene, 33647

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integrin complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
receptor complex ISO
Inferred from Sequence Orthology
more info
PubMed 
Preferred Names
integrin beta-6
Names
integrin beta-6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159564.1NP_001153036.1  integrin beta-6 precursor

    See identical proteins and their annotated locations for NP_001153036.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    AK036439, AL928546
    Consensus CDS
    CCDS16060.1
    UniProtKB/Swiss-Prot
    Q9Z0T9
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain
  2. NM_021359.3NP_067334.1  integrin beta-6 precursor

    See identical proteins and their annotated locations for NP_067334.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    AK008867, AK036439, AL928546
    Consensus CDS
    CCDS16060.1
    UniProtKB/Swiss-Prot
    Q9Z0T9
    Related
    ENSMUSP00000054944, OTTMUSP00000013748, ENSMUST00000059888, OTTMUST00000030629
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    60598292..60722603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498808.2XP_006498871.1  

    See identical proteins and their annotated locations for XP_006498871.1

    UniProtKB/Swiss-Prot
    Q9Z0T9
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain
  2. XM_006498809.1XP_006498872.1  

    See identical proteins and their annotated locations for XP_006498872.1

    UniProtKB/Swiss-Prot
    Q9Z0T9
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain
  3. XM_006498811.2XP_006498874.1  

    See identical proteins and their annotated locations for XP_006498874.1

    UniProtKB/Swiss-Prot
    Q9Z0T9
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain
  4. XM_006498810.2XP_006498873.1  

    See identical proteins and their annotated locations for XP_006498873.1

    UniProtKB/Swiss-Prot
    Q9Z0T9
    Conserved Domains (3) summary
    pfam08725
    Location:730775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam00362
    Location:30454
    Integrin_beta; Integrin, beta chain
    pfam07965
    Location:624706
    Integrin_B_tail; Integrin beta tail domain

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    62295485..62419857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)