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ZNF676 zinc finger protein 676 [ Homo sapiens (human) ]

Gene ID: 163223, updated on 8-May-2016
Official Symbol
ZNF676provided by HGNC
Official Full Name
zinc finger protein 676provided by HGNC
Primary source
HGNC:HGNC:20429
See related
Ensembl:ENSG00000196109 HPRD:17313; Vega:OTTHUMG00000182934
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
19p12
Exon count:
12
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 19 NC_000019.10 (22178936..22248018, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (22361903..22379753, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene metadherin pseudogene Neighboring gene vomeronasal 1 receptor 85 pseudogene Neighboring gene zinc finger protein 729 Neighboring gene uncharacterized LOC105372330

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology.
NHGRI GWA Catalog
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.
NHGRI GWA Catalog
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001411.2NP_001001411.2  zinc finger protein 676

    See identical proteins and their annotated locations for NP_001001411.2

    Status: PROVISIONAL

    Source sequence(s)
    AC073539, AK097798, BX281304
    Consensus CDS
    CCDS42539.1
    UniProtKB/Swiss-Prot
    Q8N7Q3
    Related
    ENSP00000380310, OTTHUMP00000270538, ENST00000397121, OTTHUMT00000464392
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p2 Primary Assembly

    Range
    22178936..22248018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527735.1XP_011526037.1  

    See identical proteins and their annotated locations for XP_011526037.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011527737.1XP_011526039.1  

    See identical proteins and their annotated locations for XP_011526039.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011527733.1XP_011526035.1  

    See identical proteins and their annotated locations for XP_011526035.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_011527736.1XP_011526038.1  

    See identical proteins and their annotated locations for XP_011526038.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_011527734.1XP_011526036.1  

    See identical proteins and their annotated locations for XP_011526036.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011527732.1XP_011526034.1  

    See identical proteins and their annotated locations for XP_011526034.1

    Conserved Domains (6) summary
    cd07765
    Location:1554
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:1575
    KRAB; krueppel associated box
    COG5048
    Location:238623
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:590615
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:550570
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:157178
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_011527740.1XP_011526042.1  

    See identical proteins and their annotated locations for XP_011526042.1

    Conserved Domains (6) summary
    cd07765
    Location:443
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:227612
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:579604
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:539559
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:146167
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_011527739.1XP_011526041.1  

    See identical proteins and their annotated locations for XP_011526041.1

    Conserved Domains (4) summary
    COG5048
    Location:130515
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:482507
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:442462
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:4970
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_011527738.1XP_011526040.1  

    See identical proteins and their annotated locations for XP_011526040.1

    Conserved Domains (4) summary
    COG5048
    Location:163548
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:515540
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:475495
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:82103
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_936161.1 RNA Sequence

  2. XR_936160.1 RNA Sequence

  3. XR_936162.1 RNA Sequence

Reference GRCh38.p2 ALT_REF_LOCI_1

Genomic

  1. NW_003315965.1 Reference GRCh38.p2 ALT_REF_LOCI_1

    Range
    52649..129938
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011547027.1XP_011545329.1  

    See identical proteins and their annotated locations for XP_011545329.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011547026.1XP_011545328.1  

    See identical proteins and their annotated locations for XP_011545328.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011547028.1XP_011545330.1  

    See identical proteins and their annotated locations for XP_011545330.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_011547025.1XP_011545327.1  

    See identical proteins and their annotated locations for XP_011545327.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_011547029.1XP_011545331.1  

    See identical proteins and their annotated locations for XP_011545331.1

    UniProtKB/Swiss-Prot
    Q8N7Q3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_005276953.2XP_005277010.1  

    See identical proteins and their annotated locations for XP_005277010.1

    Conserved Domains (6) summary
    cd07765
    Location:443
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:227612
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:579604
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:539559
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:146167
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_011547024.1XP_011545326.1  

    See identical proteins and their annotated locations for XP_011545326.1

    Conserved Domains (6) summary
    cd07765
    Location:1554
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:1575
    KRAB; krueppel associated box
    COG5048
    Location:238623
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:590615
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:550570
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:157178
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_011547030.1XP_011545332.1  

    See identical proteins and their annotated locations for XP_011545332.1

    Conserved Domains (4) summary
    COG5048
    Location:163548
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:515540
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:475495
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:82103
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_011547031.1XP_011545333.1  

    See identical proteins and their annotated locations for XP_011545333.1

    Conserved Domains (4) summary
    COG5048
    Location:130515
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:482507
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:442462
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:4970
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_952170.1 RNA Sequence

  2. XR_952169.1 RNA Sequence

  3. XR_952171.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    22361538..22379442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)