Format

Send to:

Choose Destination

STOML3 stomatin like 3 [ Homo sapiens (human) ]

Gene ID: 161003, updated on 26-May-2016
Official Symbol
STOML3provided by HGNC
Official Full Name
stomatin like 3provided by HGNC
Primary source
HGNC:HGNC:19420
See related
Ensembl:ENSG00000133115 HPRD:16315; MIM:608327; Vega:OTTHUMG00000016763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SRO; Epb7.2l
Orthologs
Location:
13q13.3
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 13 NC_000013.11 (38965925..38990859, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (39540062..39564996, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group XIIA pseudogene 2 Neighboring gene ankyrin repeat domain 26 pseudogene 2 Neighboring gene proline and serine rich 1 Neighboring gene NHL repeat containing 3

NHGRI GWAS Catalog

Description
A genome-wide association study of the metabolic syndrome in Indian Asian men.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cilium IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
stomatin-like protein 3
Names
EPB72-like 3
SLP-3
erythrocyte band 7 integral membrane protein
protein 7.2B
stomatin (EPB72)-like 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144033.1NP_001137505.1  stomatin-like protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001137505.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an additional in-frame coding exon compared to transcript variant 1. This results in translation initiation from a downstream AUG found in this novel exon, and a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AK304159, BC025760, BM982114, DB200356
    Consensus CDS
    CCDS45040.1
    UniProtKB/Swiss-Prot
    Q8TAV4
    Related
    ENSP00000401989, ENST00000423210
    Conserved Domains (2) summary
    COG0330
    Location:22257
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
    cl19107
    Location:64262
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  2. NM_145286.2NP_660329.1  stomatin-like protein 3 isoform 1

    See identical proteins and their annotated locations for NP_660329.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK304159, BC025760, BM982114
    Consensus CDS
    CCDS9367.1
    UniProtKB/Swiss-Prot
    Q8TAV4
    Related
    ENSP00000368952, OTTHUMP00000018290, ENST00000379631, OTTHUMT00000044604
    Conserved Domains (2) summary
    COG0330
    Location:31266
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
    cl19107
    Location:73271
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p2 Primary Assembly

    Range
    38965925..38990859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011534946.1XP_011533248.1  

    Conserved Domains (2) summary
    COG0330
    Location:31274
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
    cl19107
    Location:73279
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  2. XM_011534947.1XP_011533249.1  

    Conserved Domains (2) summary
    COG0330
    Location:3203
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
    cl19107
    Location:6208
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

Alternate CHM1_1.1

Genomic

  1. NC_018924.2 Alternate CHM1_1.1

    Range
    39508098..39532961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)