Format

Send to:

Choose Destination

CREBRF CREB3 regulatory factor [ Homo sapiens (human) ]

Gene ID: 153222, updated on 26-May-2016
Official Symbol
CREBRFprovided by HGNC
Official Full Name
CREB3 regulatory factorprovided by HGNC
Primary source
HGNC:HGNC:24050
See related
Ensembl:ENSG00000164463 HPRD:17308; Vega:OTTHUMG00000163322
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRF; C5orf41
Orthologs
Location:
5q35.1
Exon count:
10
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 5 NC_000005.10 (173056349..173139293)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (172483355..172566291)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene pyrophosphatase (inorganic) 1 pseudogene Neighboring gene ATPase H+ transporting V0 subunit e1 Neighboring gene small nucleolar RNA, H/ACA box 74B Neighboring gene cell division cycle 42 pseudogene 5 Neighboring gene BCL2/adenovirus E1B 19kDa interacting protein 1 Neighboring gene ribosomal protein L7a pseudogene 33

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp313F2319, DKFZp686G2059

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
Preferred Names
CREB3 regulatory factor
Names
UPF0474 protein C5orf41
adult retina protein
luman recruitment factor
luman-recruiting factor
luman/CREB3 recruitment factor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168393.1NP_001161865.1  CREB3 regulatory factor isoform 2

    See identical proteins and their annotated locations for NP_001161865.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and coding region, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Both variant 2 and variant 3 encode the same isoform (2).
    Source sequence(s)
    BX647768
    Consensus CDS
    CCDS54948.1
    UniProtKB/Swiss-Prot
    Q8IUR6
    Related
    ENSP00000431107, OTTHUMP00000223582, ENST00000522692, OTTHUMT00000372669
  2. NM_001168394.1NP_001161866.1  CREB3 regulatory factor isoform 2

    See identical proteins and their annotated locations for NP_001161866.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding region, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Both variant 2 and variant 3 encode the same isoform (2).
    Source sequence(s)
    AY174896, BX647768
    Consensus CDS
    CCDS54948.1
    UniProtKB/Swiss-Prot
    Q8IUR6
    Related
    ENSP00000428290, OTTHUMP00000223583, ENST00000520420, OTTHUMT00000372670
  3. NM_153607.2NP_705835.2  CREB3 regulatory factor isoform 1

    See identical proteins and their annotated locations for NP_705835.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC008378, AY139008, BX647768
    Consensus CDS
    CCDS34293.1
    UniProtKB/Swiss-Prot
    Q8IUR6
    Related
    ENSP00000296953, OTTHUMP00000223581, ENST00000296953, OTTHUMT00000372667
    Conserved Domains (1) summary
    cd14809
    Location:525563
    bZIP_AUREO-like; Basic leucine zipper (bZIP) domain of blue light (BL) receptor aureochrome (AUREO) and similar bZIP domains

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p2 Primary Assembly

    Range
    173056349..173139293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005265821.3XP_005265878.1  

    See identical proteins and their annotated locations for XP_005265878.1

    Conserved Domains (1) summary
    cd14809
    Location:517555
    bZIP_AUREO-like; Basic leucine zipper (bZIP) domain of blue light (BL) receptor aureochrome (AUREO) and similar bZIP domains
  2. XM_011534442.1XP_011532744.1  

    See identical proteins and their annotated locations for XP_011532744.1

    Conserved Domains (1) summary
    cd14809
    Location:517555
    bZIP_AUREO-like; Basic leucine zipper (bZIP) domain of blue light (BL) receptor aureochrome (AUREO) and similar bZIP domains
  3. XM_011534441.1XP_011532743.1  

    See identical proteins and their annotated locations for XP_011532743.1

    UniProtKB/Swiss-Prot
    Q8IUR6
    Conserved Domains (1) summary
    cd14809
    Location:525563
    bZIP_AUREO-like; Basic leucine zipper (bZIP) domain of blue light (BL) receptor aureochrome (AUREO) and similar bZIP domains
  4. XM_006714822.2XP_006714885.1  

    See identical proteins and their annotated locations for XP_006714885.1

    UniProtKB/Swiss-Prot
    Q8IUR6
    Conserved Domains (1) summary
    cd14809
    Location:525563
    bZIP_AUREO-like; Basic leucine zipper (bZIP) domain of blue light (BL) receptor aureochrome (AUREO) and similar bZIP domains

Alternate CHM1_1.1

Genomic

  1. NC_018916.2 Alternate CHM1_1.1

    Range
    171916093..171998823
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)