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Mnx1 motor neuron and pancreas homeobox 1 [ Mus musculus (house mouse) ]

Gene ID: 15285, updated on 19-Dec-2014
Official Symbol
Mnx1provided by MGI
Official Full Name
motor neuron and pancreas homeobox 1provided by MGI
Primary source
MGI:MGI:109160
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HB9; MNR2; Hlxb9
See Mnx1 in Epigenomics, MapViewer
Location:
5 B1; 5
Exon count:
3
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (29473823..29478470, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36086 Neighboring gene nucleolar protein with MIF4G domain 1 Neighboring gene developmental pluripotency associated 5 pseudogene Neighboring gene ubiquitin protein ligase E3C

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Maturity onset diabetes of the young, organism-specific biosystem (from KEGG)
    Maturity onset diabetes of the young, organism-specific biosystemAbout 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal dominant inheritance. This monogenic form of type II diabetes is called maturity onset diabetes of the young (MO...
  • Maturity onset diabetes of the young, conserved biosystem (from KEGG)
    Maturity onset diabetes of the young, conserved biosystemAbout 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal dominant inheritance. This monogenic form of type II diabetes is called maturity onset diabetes of the young (MO...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell morphogenesis involved in neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
central nervous system neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
diaphragm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral neural tube patterning IDA
Inferred from Direct Assay
more info
PubMed 
endocrine pancreas development IMP
Inferred from Mutant Phenotype
more info
PubMed 
motor neuron axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
nerve development IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron projection morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
pancreas development IMP
Inferred from Mutant Phenotype
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
respiratory system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
spinal cord motor neuron cell fate specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
motor neuron and pancreas homeobox protein 1
Names
motor neuron and pancreas homeobox protein 1
homeobox gene HB9
homeobox protein HB9

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019944.2NP_064328.2  motor neuron and pancreas homeobox protein 1

    See proteins identical to NP_064328.2

    Status: VALIDATED

    Source sequence(s)
    BC132283, BE648171
    Consensus CDS
    CCDS19150.1
    UniProtKB/TrEMBL
    A2RSX2
    Conserved Domains (1) summary
    cd00086
    Location:242300
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    29473823..29478470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    26989654..26994301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)